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Management of Hepatocellular Carcinoma: Bangladesh Perspective

Sheikh M Noor-E-Alam1

  • 1Department of Hepatology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh.

Euroasian Journal of Hepato-Gastroenterology
|July 3, 2018
PubMed

Insights

Hepatocellular carcinoma (HCC) is a major health concern in Bangladesh, ranking as the third most common cancer. Hepatitis B virus (HBV) significantly contributes to HCC development, underscoring the need for focused management strategies.

Area of Science:

  • Hepatology
  • Oncology
  • Public Health

Background:

  • Hepatocellular carcinoma (HCC) presents a substantial disease burden in Bangladesh.
  • HCC is the third most prevalent cancer, following lung and stomach cancers.
  • Liver diseases account for 8-12% of medical admissions in public hospitals.

Purpose of the Study:

  • To review the impact of Hepatitis B virus (HBV) and Hepatitis C virus (HCV) on HCC development.
  • To discuss the management of HCC within the context of Bangladesh.

Main Methods:

  • Mini-review of existing literature and data.
  • Analysis of HBV and HCV prevalence and their association with HCC.
  • Examination of current HCC management practices in Bangladesh.

Main Results:

  • Hepatitis B virus (HBV) is implicated in 66% of HCC cases in Bangladesh.
  • Estimated HBV and HCV prevalence rates are 5.4% and 0.84%, respectively.
  • Significant contribution of viral hepatitis to liver disease and HCC.

Conclusions:

  • HBV and HCV are critical factors in the etiology of HCC in Bangladesh.
  • Effective management strategies for HCC are essential, considering the high prevalence of viral hepatitis.
  • Further research and public health interventions are needed to combat HCC in the region.

Keywords:
BangladeshInnovative cancer therapyLiver cancerManagement.

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