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Short and Long-Term Effects of Compromised Birth Weight, Head Circumference, and Apgar Scores on Neuropsychological
Stephanie B Gampel1,2, Yoko Nomura2,3
1Albert Einstein College of Medicine, New York, USA.
Insights
Small head circumference and low Apgar scores predict later developmental issues, including physical, neurological, cognitive, and psychological deficits. These factors, alongside low birth weight, can help screen for future health problems.
Area of Science:
- Perinatal health
- Developmental pediatrics
- Child psychology
Background:
- Low birth weight (LBW) is a known risk factor for developmental deficits.
- Limited research exists on small head circumference and low 5-minute Apgar scores as predictors of developmental abnormalities.
Purpose of the Study:
- To determine if small head circumference and low 5-minute Apgar scores predict developmental abnormalities.
- To assess the long-term impact of these perinatal factors on physical, neurological, cognitive, and psychological functioning.
Main Methods:
- Longitudinal study of 2,151 individuals.
- Assessed physical, neurological, cognitive, and psychological functioning.
- Examined the association with low birth weight, small head circumference, and low Apgar scores.
Main Results:
- Small head circumference and low Apgar scores correlated with increased hospital visits and neurological abnormalities at age 1.
- Lower IQ scores at ages 4 and 7 were observed in individuals with small head circumference or low Apgar scores.
- Higher incidence of adult anxiety was linked to small head circumference and low Apgar scores.
Conclusions:
- Small head circumference and low Apgar scores are significant predictors of later developmental abnormalities.
- These factors can complement low birth weight in screening for future developmental deficits.
- Early identification using these markers can aid in timely intervention and support.
Background:
Low birth weight (LBW, <2500 g) is an adverse perinatal risk that may reflect a poor intrauterine environment. While LBW has been a well-known predictor of physical, neurological, cognitive and psychological deficits later in life, minimal research has been done on small head circumference and low 5 minute Apgar scores, and their association with subsequent developmental abnormalities.
Objective:
The current study aims to demonstrate that small head circumference and low 5-minute Apgar scores are predictors for developmental abnormalities throughout childhood and later.
Methods:
Using a longitudinal design, 2,151 individuals' physical, neurological, and cognitive functioning in childhood, as well as psychological functioning in adulthood, was assessed as a function of three perinatal risk factors: LBW, small head circumference and low Apgar scores.
Results:
Similar to findings with LBW, small head circumference or a low Apgar score were associated with increased number of hospital visits (p<0.0001 and p=0.005 respectively) and neurological abnormalities (p<0.0001 and p=0.001 respectively) at age 1. Intelligence quotient (IQ) scores at ages 4 and 7 were significantly lower for those born with small head circumference (p<0.0001) or low Apgar scores (p=0.002). Finally, the incidence of anxiety in adulthood was significantly higher for those born with small head circumference (p=0.03) or low Apgar scores (p=0.004) compared to their counterpart.
Conclusion:
Small head circumference and low a Apgar score are predictors of later physical, neurological, cognitive and psychological abnormalities, and can complement LBW, a more frequently used perinatal risk factor, and thus be used to screen for future developmental deficits, together with LBW.
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