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Author Spotlight: Exploring the Role of FAM83A in Cervical Cancer
Published on: February 9, 2024
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A Study on Cervical Cancer Screening Using Pap Smear Test and Clinical Correlation
Pushp Lata Sachan1, Meenakshi Singh2, Munna Lal Patel3
1Department of Physiology, Career Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.
Asia-Pacific Journal of Oncology Nursing
|July 3, 2018
Summary
The Pap smear is an effective screening tool for detecting precancerous cervical lesions in gynecological patients. Abnormal results necessitate further investigation with colposcopy and biopsy for accurate diagnosis and management.
Area of Science:
- Gynecology
- Cytopathology
- Oncology
Background:
- Cervical cancer screening is crucial for early detection of precancerous lesions.
- The Pap smear (Papanicolaou test) is a widely used method for cervical cancer screening.
Purpose of the Study:
- To evaluate the effectiveness of the Pap smear for detecting precancerous cervical lesions.
- To assess the prevalence of abnormal Pap smear findings in a gynecological patient population.
Main Methods:
- A study involving 1650 sexually active women aged over 21 years was conducted.
- Pap smears were collected and cytopathologically examined to screen for cervical cancer.
- Women with visible malignant lesions were excluded; those with abnormal results underwent colposcopy and biopsy.
Main Results:
- The Pap smear test was adequate in 93.57% of women; 6.42% had inadequate samples.
- Results showed 48.84% negative for malignancy, 42.66% with infection/inflammation.
- Precancerous lesions were detected: Atypical Squamous Cells of Undetermined Significance (ASCUS) in 2.90%, Low-Grade Squamous Intraepithelial Lesion (LSIL) in 5.09%, and High-Grade Squamous Intraepithelial Lesion (HSIL) in 0.48%.
Conclusions:
- The Pap smear is a simple, noninvasive, and cost-effective method for detecting precancerous cervical lesions.
- Abnormal Pap test results warrant colposcopy, with biopsy recommended for abnormal colposcopy findings.
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