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[FAMILY, IMMIGRATION AND QUALITY OF TREATMENT: GENETIC AND ENVIRONMENTAL EFFECTS ON COMPLICATIONS IN DIABETES]
Margarita Fraimovitch1, Julio Weinstein2
1Meuhedet Health Fund.
Background:
There is a variety of native and foreign-born diabetes patients from all over the world in Israel. A combination of genetic and acquired factors leads to high-rate spreading of diabetes mellitus. Consequently, certain differences exist in a number of features of the disease typical for Israeli-born patients and for immigrants.
Methods:
This retrospective research has been conducted within a population of diabetes patients aged over 40 years in a group of immigrant and a group of Israeli-born patients (119 immigrants and 65 Israeli-born patients). Parameters checked were: background diseases, family history, types of treatment, risk factors and complications.
Results:
In the group of immigrants, the percentage of male patients with negative family history was much higher than the percentage of male patients with positive family history of diabetes mellitus (16.8% vs. 6.5% respectively). Relating immigrants with positive family history, micro-vascular complications were 3 times more prevalent than macro-vascular complications (30.3% vs. 9.2% respectively). In the group of Israeli-born patients there was a significant difference in the level of micro- and macro-vascular complications among the patients with positive and negative family history (32% vs. 12.3% for macro-vascular and 27.7 vs. 10.8% for micro-vascular complications).
Conclusions:
(1) The percentage of males suffering from diabetes mellitus with negative family history is much higher than that with positive family history (16.8% vs. 6.5%); (2) The level of micro-vascular complications among immigrants with positive family history is 3.3 times higher than the level of macro-vascular complications among immigrants with positive family history of diabetes mellitus (30.3% vs. 9.2%).
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