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Steps for the Autologous Ex vivo Perfused Porcine Liver-kidney Experiment
Published on: December 18, 2013
[Liver and Kidney Function of E-waste Dismantling Workers and Potential Influencing Factors]
Xiao Yan1, Shu-Yuan Li1, Mei-Huan Wang1
1State Environmental Protection Key Laboratory of Environmental Pollution Health Risk Assessment, South China Institute of Environmental Sciences, Guangzhou 510655, China.
Abstract:
High levels of exposure to heavy metals and persistent organic pollutants (POPs) by e-waste dismantling workers has attracted increasing attention, but the health conditions of the workers are seldom reported. The liver and kidney functions of the workers were studied by comparing the blood indicators of the worker group with those of the control group. Moreover, factors affecting the liver and kidney functions, such as the sexuality, age, and working time, were identified using correlation analysis. The ratio of aspartate transaminase and alanine aminotransferase (AST/ALT) and the direct bilirubin (DBIL) of the workers were significantly lower than the control group but the abnormal rate of liver and kidney remained the same in both groups. The abnormal rates of liver and kidney were higher in men than in women. ALT, AST/ALT, and urea nitrogen (BUN) increased with age while creatinine (CREA) increased with working time. The factors of liver and kidney damage caused by POPs and DBIL can be used as the indicators of the damage caused by multi-factors.
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