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Cervical myelography with metrizamide using lumbar injection.

O Sortland1

  • 1Department of Radiology, University Hospital, Oslo, Norway.

Acta Radiologica. Supplementum
|January 1, 1977
PubMed
Summary
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Cervical myelography using metrizamide (Amipaque) via lumbar injection is effective, though common side effects include headache and nausea. Major complications like seizures are rare, occurring in only one patient out of 260 procedures.

Area of Science:

  • Radiology
  • Neurology
  • Pharmacology

Background:

  • Cervical myelography is a diagnostic imaging technique.
  • Metrizamide (Amipaque) is a contrast agent used in myelography.
  • Evaluating the safety and efficacy of contrast agents is crucial.

Purpose of the Study:

  • To assess the technique, film quality, and side effect frequency of cervical myelography.
  • To evaluate the safety profile of metrizamide (Amipaque) in lumbar injection for cervical myelography.

Main Methods:

  • A consecutive series of 100 cervical myelographies using lumbar injection of metrizamide (Amipaque).
  • Evaluation of the imaging technique, quality of diagnostic films, and patient-reported adverse effects.
  • Monitoring for neurological and electroencephalographic (EEG) changes.

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Main Results:

  • The most frequent adverse effects were headache (47%) and nausea/vomiting (27%).
  • EEG disturbances were observed in 20% of patients.
  • One patient experienced major complications (grand mal seizures, mental confusion), representing the sole major event in 260 procedures.

Conclusions:

  • Cervical myelography with lumbar metrizamide injection is a viable technique with generally manageable side effects.
  • The incidence of serious complications is low, making it a relatively safe procedure.
  • Further research may focus on mitigating common adverse effects like headache and nausea.