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Pediatric myelography with metrizamide.

C R Fitz1, D C Harwood-Nash, J F Barry

  • 1Department of Radiology, Hospital for Sick Children, Toronto, Ontario, Canada.

Acta Radiologica. Supplementum
|January 1, 1977
PubMed
Summary
This summary is machine-generated.

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Metrizamide myelography in children showed comparable quality to iophendylate but with more side effects. However, its absorption and improved conus visualization offer examination advantages.

Area of Science:

  • Pediatric Radiology
  • Neuroradiology
  • Diagnostic Imaging

Background:

  • Metrizamide (Amipaque) is a non-ionic water-soluble contrast medium used in myelography.
  • Oily contrast media like iophendylate have traditionally been used but require removal.
  • Assessing the efficacy and safety of metrizamide in pediatric patients is crucial.

Purpose of the Study:

  • To evaluate the quality and safety of metrizamide myelography in pediatric patients.
  • To compare metrizamide with traditional oily contrast media in pediatric lumbar-low thoracic examinations.

Main Methods:

  • Ninety-four children underwent myelography using metrizamide.
  • Examinations focused on the lumbar-low thoracic region.
  • Quality of imaging and side effects were documented.

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Main Results:

  • Metrizamide provided generally equivalent image quality to iophendylate in the lumbar-low thoracic region.
  • Side effects, including nausea, vomiting, and fever, were more frequent with metrizamide compared to iophendylate and previously reported adult data.
  • Metrizamide's absorption eliminated the need for removal, and it improved conus visualization in the prone position.
  • Facilitated post-myelography computed scanning.

Conclusions:

  • Metrizamide is a viable alternative to oily contrast media for pediatric myelography, offering advantages in contrast absorption and conus visualization.
  • Increased incidence of side effects in children necessitates careful consideration and monitoring.
  • The ability to combine metrizamide myelography with CT scanning enhances diagnostic capabilities.