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Updated: Feb 8, 2026

07:16
Isolation of Cancer Stem Cells From Human Prostate Cancer Samples
Published on: March 14, 2014
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Macropinocytosis Fuels Prostate Cancer
Cosimo Commisso1, Jayanta Debnath2
1Tumor Initiation and Maintenance Program, NCI-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California. jayanta.debnath@ucsf.edu ccommisso@sbpdiscovery.org.
Cancer Discovery
|July 4, 2018
Abstract:
Kim and colleagues identify necrotic debris as a macropinocytic cargo in PTEN-deficient prostate cancer cells, which is catabolized to generate the nutrients and biomass necessary to support tumor cell growth and metabolism in nutrient-limiting conditions.
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