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Related Experiment Videos

Interfering with inhibition may improve motor function.

G A Robinson, M E Goldberger

    Brain Research
    |November 4, 1985
    PubMed
    Summary
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    Spinal transection in cats reveals suppressed motor behaviors. Blocking GABAergic inhibition improves motor function recovery, highlighting the role of inhibitory processes in motor development and neurological damage.

    Area of Science:

    • Neuroscience
    • Developmental Neuroscience
    • Motor Control

    Background:

    • Motor behaviors present in newborn cats are typically suppressed.
    • Spinal transection can reveal these suppressed motor behaviors.

    Purpose of the Study:

    • To investigate the role of inhibitory processes in normal motor development.
    • To understand the influence of inhibitory processes on motor function recovery after neurological damage.

    Main Methods:

    • Spinal transection in newborn cats.
    • Assessment of motor performance in adult spinal cats.
    • Pharmacological blockade of GABAergic inhibition in adult spinal cats.

    Main Results:

    • Spinal kittens, after reaching adulthood, exhibit superior motor performance compared to chronically operated adult spinal cats.

    Related Experiment Videos

  • Blocking GABAergic inhibition significantly improves motor performance in chronically operated adult spinal cats.

    • Conclusions:

    • Inhibitory processes play a crucial role in suppressing motor behaviors during normal development.
    • Inhibitory processes significantly impact the recovery of motor function following neurological damage.