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Updated: Feb 8, 2026

Power Input Measurements in Stirred Bioreactors at Laboratory Scale
Published on: May 16, 2018
The role of laboratory-scale bioreactors at the semi-continuous and continuous microbiological and biotechnological
T S Tikhomirova1, M S Taraskevich2, O V Ponomarenko2
1Institute for Biological Instrumentation, Russian Academy of Science, Pushchino, Moscow Region, 142290, Russia. tts05@mail.ru.
Abstract:
Laboratory-scale bioreactors represent an important part of microbiological, biotechnological, and biochemical researches. The small volume bioreactors enable the biomass growth, extracellular metabolite production, solid-state fermentation, and biocatalytic processes in a controlled open system. Using the lab-scale bioreactors, the processes which were optimized in experiments can be scaled up to a pilot level. In turn, the manufacturing scale processes can be scaled down to study the heterogeneity of the system and its effect on the producer. This mini-review is focused on a short description of features of the most popular designs of continuous and semi-continuous bioreactors applied at the present time as well as their application area.
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