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Updated: Feb 8, 2026

A Modified Method for Heterotopic Mouse Heart Transplantion
Published on: June 23, 2014
The Past, Present and Future of Heart Transplantation
In Cheol Kim1, Jong Chan Youn2, Jon A Kobashigawa3
1Division of Cardiology, Keimyung University Dongsan Medical Center, Daegu, Korea.
Abstract:
Heart transplantation (HTx) has become standard treatment for selected patients with end-stage heart failure. Improvements in immunosuppressant, donor procurement, surgical techniques, and post-HTx care have resulted in a substantial decrease in acute allograft rejection, which had previously significantly limited survival of HTx recipients. However, limitations to long-term allograft survival exist, including rejection, infection, coronary allograft vasculopathy, and malignancy. Careful balance of immunosuppressive therapy and vigilant surveillance for complications can further improve long-term outcomes of HTx recipients.
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