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Updated: Feb 8, 2026
07:45
Retroductal Nanoparticle Injection to the Murine Submandibular Gland
Published on: May 3, 2018
10.8K
Untreated submandibular megalith for over 60 years
Khalid A Ahmed1, Alia K Alfadhel, Bayan J Mohammed
1Al-Farabi College for Dentistry and Nursing, Riyadh, Kingdom of Saudi Arabia. E-mail. dr.k_ahmed@hotmail.com.
Saudi Medical Journal
|July 4, 2018
Summary
Intra-glandular sialolithiasis, a rare salivary gland disorder, caused chronic submandibular swelling and infection in an 85-year-old male. This case highlights the largest and longest-standing intra-glandular submandibular stone reported.
Area of Science:
- Oral and Maxillofacial Surgery
- Pathology of Salivary Glands
Background:
- Intra-parenchymal sialolithiasis is a rare condition affecting salivary glands.
- Submandibular gland fibrosis can result from chronic sialolithiasis, causing pain, swelling, and infection.
Observation:
- An 85-year-old Saudi male presented with a 60-year history of recurrent left submandibular swelling and infection.
- The condition was repeatedly misdiagnosed as dental infection, infected sebaceous cyst, or lipoma.
Findings:
- The patient had the largest intra-glandular submandibular stone ever documented.
- Histopathological examination revealed significant fibrosis of the submandibular gland.
Implications:
- This case underscores the importance of considering rare salivary gland pathologies in chronic submandibular region issues.
- Accurate diagnosis of intra-parenchymal sialolithiasis is crucial for effective management and preventing complications like fibrosis.
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