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Updated: Feb 8, 2026

Synthesis and Evaluation of a Ruthenium-based Mitochondrial Calcium Uptake Inhibitor
Published on: October 26, 2017
Luminescent Tetrahedral Molecular Cages Containing Ruthenium(II) Chromophores
Ena T Luis1, Hasti Iranmanesh1, Kasun S A Arachchige1
1School of Chemistry , UNSW Sydney , Sydney , 2052 Australia.
Abstract:
We have designed linear metalloligands which contain a central photoactive [Ru(N∧N)3]2+ unit bordered by peripheral metal binding sites. The combination of these metalloligands with Zn(II) and Fe(II) ions leads to heterometallic tetrahedral cages, which were studied by NMR spectroscopy, mass spectrometry, and photophysical methods. Like the parent metalloligands, the cages remain emissive in solution. This approach allows direct incorporation of the favorable properties of ruthenium(II) polypyridyl complexes into larger self-assembled structures.
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