Related Experiment Video
Updated: Feb 8, 2026

Synovial Fluid Analysis to Identify Osteoarthritis
Published on: October 20, 2022
Treatment of cardiac synovial sarcoma: experience of two cases
Antonella Coli1, Giovanni Alfonso Chiariello2, Mariangela Novello3
1Institute of Anatomic Pathology, Catholic University of Sacred Heart, Largo F. Vito 1, 00168, Rome, Italy. Antonella.Coli@unicatt.it.
Background:
Primary heart sarcomas are exceedingly rare tumors. Among primary cardiac sarcomas, synovial sarcoma is one of the rarest, involving cardiac cavities or pericardium.
Case Presentation:
Two cases of synovial sarcoma are presented with the clinical course and therapy. Both cases were treated with surgery and chemo/radiotherapy. Interestingly, one of the patient, a 52-year-old male with an intracardiac synovial sarcoma, undergone a SynCardia total artificial heart implantation, but died for multiple pulmonary metastases waiting for transplantation.
Conclusion:
Complete surgical resection of cardiac synovial sarcoma is the gold standard of therapy, though rarely possible. Although guidelines for the treatment are not well established, due to limited number of cases reported, chemotherapy and radiotherapy are frequently administered and seem to prolong mean patient's survival. Cardiac transplantation could be considered in selected cases.
Related Concept Videos
Structural Joints: Synovial Joints
Development of the Limb Synovial Joints
The mesenchymal stem cells differentiate into chondrocytes that form the hyaline cartilage, and later the cartilaginous model of the bone. This model further transforms into a bone. This process is known as endochondral ossification.
During development, the limbs...
What is an Experiment?
Rous Sarcoma Virus (RSV) and Cancer
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...
Thomson's e/m Experiment
A particle with charge q, speed v, and mass m enters an area from the top, where the magnetic and electric fields are perpendicular both to the particle's motion and to one another. The magnetic...
Controls in Experiments

