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Disseminated intravascular coagulation syndrome.
International Journal of Oral Surgery
|October 1, 1985
Summary
Malignant tumors can trigger disseminated intravascular coagulation (DIC), a serious bleeding disorder. While heparin and aprotinin showed some benefit, neither patient was cured, highlighting treatment challenges.
Area of Science:
- Oncology
- Hematology
Background:
- Disseminated intravascular coagulation (DIC) is a complex condition involving abnormal blood clotting.
- Malignant tumors are increasingly recognized as potential triggers for DIC.
Observation:
- Two cases of DIC are presented: one in a patient with malignant fibrous histiocytoma of the maxilla and another with squamous cell cancer of the tongue.
- Triggers identified included malignant tumor, infection, shock, and surgical procedures.
Findings:
- Heparin and aprotinin were administered to both patients.
- Hemostatic improvement was observed in the patient with tongue cancer, but neither case achieved a cure.
- The study discusses the etiology, diagnosis, and treatment of DIC in the context of malignancy.
Implications:
- This case series underscores the critical link between malignancy and DIC.
- Effective treatment strategies for malignancy-associated DIC remain a significant clinical challenge.
- Further research is needed to improve outcomes for patients with DIC triggered by cancer.