Oocyte in vitro maturation: A sytematic review

Area of Science:

• Reproductive Medicine
• Assisted Reproductive Technology
• Gynecology

Background:

• In vitro maturation (IVM) remains a controversial aspect of assisted reproductive technology (ART).
• Despite extensive research, IVM is not yet a conventional treatment, often positioned as an alternative therapy.
• Emerging evidence supports IVM's applicability across various ART scenarios, including fertility preservation and managing Ovarian Hyperstimulation Syndrome (OHSS).

Purpose of the Study:

• To provide a comprehensive overview of the current knowledge regarding in vitro maturation (IVM).
• To examine the historical evolution and advancements of both IVM and in vitro fertilization (IVF).
• To address all facets of IVM treatment within the context of assisted reproduction.

Main Methods:

• Systematic review of existing literature on IVM and IVF.
• Analysis of studies detailing IVM's efficacy and applications.
• Examination of the developmental trajectory of IVM techniques and their integration with IVF.

Main Results:

• IVM demonstrates significant potential in fertility protection strategies.
• IVM is effective in managing Ovarian Hyperstimulation Syndrome (OHSS).
• The application scope of IVM is comparable to that of conventional in vitro fertilization (IVF).

Conclusions:

• In vitro maturation (IVM) is a viable alternative and complementary treatment in assisted reproductive technology.
• IVM plays a crucial role in fertility preservation and OHSS management.
• Continued research and clinical integration are expanding the role of IVM alongside IVF.