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Updated: Feb 8, 2026

Preparation of Contiguous Bisaziridines for Regioselective Ring-Opening Reactions
Published on: July 28, 2022
Iridium-Induced Regioselective B-H and C-C Activations at Azo-Substituted o-Carboranes
Yang Gao1, Peng-Fei Cui1, Francisco Aznarez1
1State Key Laboratory of Molecular Engineering of Polymers, Collaborative Innovation Center of Chemistry for Energy Materials, Department of Chemistry, Fudan University, Shanghai, 200433, P.R. China.
Abstract:
p-Methoxybenzeneazo-substituted o-carboranes have been synthesized and their reactivity with half-sandwich iridium and rhodium complexes has been investigated in detail. A variety of solvent- and base-dependent, highly site-selective B-H and C-C σ-bond activations at the C/B cage have been observed. While the use of CH3 OH leads to the formation of metallacarboranes, o-carborane clusters undergo cyclometallation reactions involving B(6)-H, B(4)-H or a rare B(7)-H activation in CH2 Cl2 . The synthesis of a unique pseudo-closo-iridacarborane through a very unconventional metal-mediated Ccage -Ccage activation is described in this contribution.
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