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Oncofertility-An emerging discipline rather than a special consideration
Antoinette Anazodo1,2,3, Lauren Ataman-Millhouse4, Yasmin Jayasinghe5,6
1Kids Cancer Centre, Sydney Children's Hospital, Sydney, Australia.
Oncofertility, including endocrine health and fertility preservation, is crucial for cancer patients of reproductive age. This review highlights key considerations for assessing reproductive risk and developing oncofertility services for adolescents and young adults (AYAs).
Area of Science:
- Reproductive Endocrinology
- Oncology
- Adolescent and Young Adult (AYA) Health
Background:
- Oncofertility has evolved from a quality-of-life consideration to an essential component of cancer care for reproductive-aged patients.
- It encompasses endocrine health, pubertal transitions, bone health, and menstrual health, requiring interdisciplinary collaboration.
- Adolescents and young adults (AYAs) face unique challenges regarding fertility preservation during cancer treatment.
Purpose of the Study:
- To review essential considerations for assessing reproductive risk in cancer patients.
- To summarize fertility preservation options available for AYAs undergoing cancer treatment.
- To outline key factors in developing comprehensive oncofertility services for AYAs.
Main Methods:
- This is a review article, synthesizing existing literature and guidelines.
- It focuses on the assessment of reproductive risk and fertility preservation strategies.
- Considerations for service development in oncofertility for AYAs are discussed.
Main Results:
- Oncofertility management is integral to holistic cancer care for reproductive-aged individuals.
- Comprehensive assessment includes endocrine function, pubertal status, bone health, and menstrual cyclicity.
- Effective fertility preservation strategies and tailored oncofertility services are vital for AYAs.
Conclusions:
- Oncofertility should be a standard part of cancer treatment planning for reproductive-aged patients, especially AYAs.
- Interdisciplinary teams are essential for addressing the complex reproductive health needs of these patients.
- Developing robust oncofertility services is critical for improving long-term outcomes and quality of life.
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