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Sleep and salivary cortisol in preterm neonates: a clinical, randomized, controlled, crossover study

Fabrícia Magalhães Araújo1, Mavilde da Luz Gonçalves Pedreira1, Ariane Ferreira Machado Avelar1

  • 1Universidade Federal de São Paulo, Escola Paulista de Enfermagem. São Paulo, Brazil.

Revista Brasileira De Enfermagem
|July 5, 2018
PubMed

Insights

Ear protectors did not significantly alter salivary cortisol levels or total sleep time in preterm infants. This study found no relationship between cortisol and sleep duration in the neonatal intermediate care unit.

Area of Science:

  • Neonatal care
  • Pediatric sleep science
  • Endocrinology

Background:

  • Preterm neonates experience altered sleep-wake cycles and stress responses.
  • Environmental management in neonatal intermediate care units (NICUs) aims to optimize infant well-being.
  • Salivary cortisol is a key biomarker for physiological stress in neonates.

Purpose of the Study:

  • To investigate the impact of ear protectors on salivary cortisol levels and total sleep time in preterm neonates.
  • To assess these effects during different environmental management periods in an NICU.

Main Methods:

  • A randomized, controlled, crossover study involving 12 preterm neonates.
  • Sleep evaluation utilized polysomnography and unstructured observation.
  • Salivary cortisol levels were measured at baseline.

Main Results:

  • No statistically significant differences were found in baseline salivary cortisol levels between groups.
  • Total sleep time did not differ significantly between the ear protector and control conditions.
  • No correlation was observed between baseline cortisol levels and total sleep time.

Conclusions:

  • The use of ear protectors in preterm neonates did not demonstrate a significant influence on salivary cortisol levels or total sleep time.
  • Findings suggest ear protection may not be a critical factor in modulating stress or sleep in this population under the studied conditions.
Abstract

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