Atrial fibrillation in acute Chagas disease acquired via oral transmission: a case report

Paulo Fernando Pimenta de Souza1, Rosane Cheble Domingues Pine2, Francisco Lúzio de Paula Ramos3

  • 1Universidade do Estado do Pará, Belém, PA, Brasil.

Insights

This case study details a 41-year-old man with acute Chagas disease who developed atrial fibrillation (AF). Treatment led to the reversion of AF to sinus rhythm, highlighting successful management of cardiac complications in Chagas disease.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Clinical Case Study

Background:

  • Atrial fibrillation (AF) is a supraventricular arrhythmia increasing thromboembolism risk.
  • Chagas disease, prevalent in the Brazilian Amazon, affects at least 50% of patients with cardiac abnormalities.
  • Approximately 3.3% of Chagas disease patients develop AF.

Observation:

  • A 41-year-old man from Muaná, Pará State, presented with a 30-day febrile illness.
  • Acute Chagas disease was confirmed via diagnostic tests.
  • Electrocardiogram revealed new-onset atrial fibrillation.

Findings:

  • The patient received antiparasitic, anti-arrhythmic, beta-blocker, and anticoagulant therapy.
  • A 9-month follow-up showed a reversion of atrial fibrillation to normal sinus rhythm.
  • This case demonstrates a positive outcome in managing cardiac complications of acute Chagas disease.

Implications:

  • Early diagnosis and comprehensive treatment are crucial for managing cardiac manifestations of Chagas disease.
  • This case highlights the potential for successful reversion of AF in acute Chagas disease patients.
  • Further research into cardiac complication management in Chagas disease is warranted.

Related Concept Videos

Amyloid Fibrils03:03

Amyloid Fibrils

Amyloid fibrils are aggregates of misfolded proteins.  Under most circumstances, misfolded proteins are either refolded by chaperone proteins or degraded by the proteasome. However, in the case of a mutation or a disease, these proteins can accumulate to form large clusters and often further assemble to form elongated fibers, called fibrils. 
Amyloid deposits were observed as early as 1639 in the liver and the spleen.   In 1854, Rudolph Virchow performed iodine staining,...
12.0K
Amyloid Fibrils03:03

Amyloid Fibrils

6.5K
Data Reporting and Recording01:24

Data Reporting and Recording

Reporting and recording are crucial in data documentation. The timely, thorough, and accurate documentation of facts is essential when recording patient data. Failure to record findings during an assessment or interpretation of a problem will result in loss of information and make the patient document unreliable. The reader is left with general impressions if the information is not specific. A recording is documenting data of the individual's health information in a traceable, secure, and...
5.5K
Fibril-associated Collagen01:11

Fibril-associated Collagen

Fibril-associated collagens are a type of collagens present in the extracellular matrix with interrupted triple helices or FACIT (Fibril-associated collagens interrupted triple-helices). FACIT help connect and attach the collagen fibrils with each other as well as with other proteins of the extracellular matrix.
For example, the type II collagen fibrils in cartilage have covalently bound type IX fibril-associated collagens at regular intervals. Other types of fibril-associated collagens are...
3.4K
Oral Cavity01:11

Oral Cavity

The oral cavity, or the mouth, is a complex structure in humans that plays a vital role in our day-to-day lives. Its role is not only in chewing and swallowing food; it also plays a role in speech and facial expressions.
Teeth: The teeth are the hardest structures in our bodies. Humans have two sets of teeth throughout their lifetime: deciduous (baby) teeth and permanent teeth. Each tooth consists of several parts: the crown (visible part), the root (embedded in the jaw), enamel (hard outer...
3.2K
Types of Reports I: Hands-off Report01:25

Types of Reports I: Hands-off Report

A hand-off report, also known as a change-of-shift report, is a crucial nursing process that ensures the smooth transition of patient care responsibilities between nursing staff.
Following are the key components and categories of hand-off reports:
Purpose and Process:
1.5K