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Biosynthesis of Polysaccharides

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Polysaccharides such as glycogen and starch are synthesized from nucleoside diphosphate sugars, primarily uridine diphosphate glucose (UDPG) and adenosine diphosphate glucose (ADPG). These activated glucose donors act as key intermediates in carbohydrate metabolism and biosynthesis. UDPG primarily involves glycogen synthesis in animals and many bacteria, while ADPG plays a fundamental role in starch synthesis in plants and certain bacteria.UDPG is formed when glucose-1-phosphate reacts with...
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In a series resistor-inductor (R-L) circuit, closing the switch at the start of the time period simulates a three-phase short circuit, a fault condition where all three phases of an unloaded synchronous machine are short-circuited. When there is no fault impedance and no initial current, the initial voltage is determined by the phase angle of the source voltage.
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A Facile and Eco-friendly Route to Fabricate PolyLactic Acid Scaffolds with Graded Pore Size
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Biosafe, Eco-Friendly Levan Polysaccharide toward Transient Electronics.

Ki Yoon Kwon1, Ju Seung Lee1, Gwan-Jin Ko2

  • 1School of Chemical Engineering, Sungkyunkwan University (SKKU), Suwon, 16419, Republic of Korea.

Small (Weinheim an Der Bergstrasse, Germany)
|July 6, 2018
PubMed
Summary
This summary is machine-generated.

Levan polysaccharide offers a new, biodegradable material for transient electronics. This cost-effective polymer dissolves programmably in water and shows biocompatibility in animal models.

Keywords:
biocompatiblebiodegradableimplantable electronicspolysaccharidetransient electronics

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Area of Science:

  • Materials Science
  • Polymer Chemistry
  • Biomedical Engineering

Background:

  • Transient electronics require novel materials for advanced applications.
  • Developing biodegradable and biocompatible materials is crucial for medical implants.

Purpose of the Study:

  • To introduce levan polysaccharide as a soft, transparent, and cost-effective material for transient electronics.
  • To investigate the dissolution properties and biocompatibility of levan.

Main Methods:

  • Chemical analysis and kinetic studies of levan hydrolysis.
  • Development of a theoretical model for levan dissolution.
  • In vivo implantation in an animal model to assess biocompatibility and dissolution control.

Main Results:

  • Levan exhibits complete and programmable dissolution in water with adjustable rates.
  • Theoretical model accurately describes reactive diffusion influenced by temperature.
  • In vivo experiments confirmed levan's non-toxicity and biocompatibility without adverse reactions.

Conclusions:

  • Levan polysaccharide is a promising material for transient electronics due to its tunable dissolution and biocompatibility.
  • Programmable dissolution control in levan enables applications in bioresorbable implants and drug delivery systems.