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Fenugreek Anaphylaxis in a Pediatric Patient
Nancy I Joseph1, Eileen Slavin2, Brian P Peppers1
1Department of Medicine, University Hospitals Cleveland Medical Center, Cleveland, OH, USA.
Allergy & Rhinology (Providence, R.I.)
|July 7, 2018
Summary
Fenugreek allergy can cause severe reactions like anaphylaxis in children. This study confirms fenugreek as a cause of food allergy through diagnostic testing.
Area of Science:
- Food Science
- Allergology
- Immunology
Background:
- Fenugreek (Trigonella foenum-graecum) is a legume widely used globally for culinary and medicinal purposes.
- Members of the Leguminosae family, including soybeans and peanuts, are known allergens.
- Fenugreek's potential as an allergen has been suspected but not definitively established.
Purpose of the Study:
- To report the first confirmed case of fenugreek-induced anaphylaxis in a pediatric patient.
- To establish fenugreek as a causative agent for allergic reactions.
- To highlight the importance of considering fenugreek in differential diagnosis of food allergies.
Main Methods:
- Case report of a pediatric patient experiencing anaphylaxis after ingesting fenugreek-containing foods.
- Diagnostic evaluation included skin prick testing (SPT) for fenugreek.
- Serum specific immunoglobulin E (sIgE) ImmunoCAP assays were performed.
Main Results:
- The pediatric patient presented with anaphylaxis symptoms post-ingestion.
- Skin testing demonstrated a positive reaction to fenugreek.
- ImmunoCAP assays confirmed elevated levels of IgE antibodies against fenugreek.
Conclusions:
- Fenugreek can cause severe allergic reactions, including anaphylaxis, in susceptible individuals.
- Diagnostic tests like SPT and sIgE assays are crucial for confirming fenugreek allergy.
- Healthcare providers should consider fenugreek allergy in pediatric patients with unexplained anaphylaxis.
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