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Cerebral Abscess by Fonsecaea monophora-The First Case Reported in Germany.

Sina Helbig1, Alexander Thuermer2, Markus Dengl3

  • 1Division of Infectious Diseases, University Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.

Open Forum Infectious Diseases
|July 7, 2018
PubMed
Summary
This summary is machine-generated.

A rare cerebral fungus, Fonsecaea monophora, was identified in a German woman without typical risk factors. This finding expands the known geographical range of this fungal infection beyond tropical regions.

Keywords:
EuropeFonsecaea monophoracerebralimmunocompetentmelanized

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Area of Science:

  • Mycology
  • Infectious Diseases
  • Neurology

Background:

  • Fonsecaea monophora is a fungus typically found in tropical regions.
  • Cerebral fungal infections are rare and can mimic brain tumors.
  • Immunocompromised individuals are usually at higher risk for such infections.

Observation:

  • A German woman without immunodeficiency or travel history presented with symptoms suggestive of a cerebral lesion.
  • Diagnostic investigations revealed an infection caused by Fonsecaea monophora in the brain.
  • This represents the first documented case in Germany and a non-tropical region.

Findings:

  • The patient was diagnosed with cerebral Fonsecaea monophora infection.
  • The case occurred in an immunocompetent individual with no history of travel to endemic areas.
  • This challenges the previous understanding of F. monophora's geographical distribution.

Implications:

  • Fonsecaea monophora infections should be considered in the differential diagnosis of cerebral tumors, even in non-tropical regions.
  • The case highlights the need to broaden the geographical awareness of this fungal pathogen.
  • Further research is needed to understand the transmission and risk factors for F. monophora in non-endemic areas.