Related Experiment Video
Updated: Feb 8, 2026
Template Directed Synthesis of Plasmonic Gold Nanotubes with Tunable IR Absorbance
Published on: April 1, 2013
Template-Directed Synthesis of an Inverted Spiro Architecture
Martin J Wanner1, Luuk Steemers1, Michiel T Uiterweerd1
1Van 't Hoff Institute for Molecular Sciences, University of Amsterdam, Science Park 904, 1098XH, Amsterdam, The Netherlands.
Abstract:
The regular bicyclic spiro motif is highly abundant given its synthetic accessibility while the diastereomer-virtually obtained through inversion at the central atom-is almost unknown. We have developed methodology to access the elusive inverted spiro architecture by employing a covalent template-directed approach. Comparison with the regular spiro bicycle analog unequivocally established the diastereomeric relationship, providing insight into the fascinating stereochemical and structural properties.
Related Concept Videos
01:20Inverting and Non-inverting OpAmps
02:05DNA as a Genetic Template
02:05DNA as a Genetic Template
01:59Lagging Strand Synthesis
There are several major differences between synthesis of the leading strand and synthesis of the lagging strand. 1) Leading strand synthesis happens in the direction of replication fork opening, whereas lagging strand synthesis happens in the...
01:14Polymer Classification: Architecture
01:15Dehydration Synthesis
Dehydration synthesis (also called a condensation reaction) is the chemical process in which two molecules covalently link together to form a new molecule, along with the release of a water molecule. Many physiologically important compounds form by dehydration synthesis reactions, such as complex carbohydrates, proteins, DNA, and RNA.
Synthesis of carbohydrates
Sugar molecules are covalently linked together by dehydration synthesis. During the reaction, the hydroxyl (-OH) group from...