Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Reproductive Cloning01:27

Reproductive Cloning

32.8K
Reproductive cloning is the process of producing a genetically identical copy—a clone—of an entire organism. While clones can be produced by splitting an early embryo—similar to what happens naturally with identical twins—cloning of adult animals is usually done by a process called somatic cell nuclear transfer (SCNT).
Somatic Cell Nuclear Transfer
In SCNT, an egg cell is taken from an animal and its nucleus is removed, creating an enucleated egg. Then a somatic...
32.8K
Genomics02:02

Genomics

40.8K
Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
40.8K
Genomic Imprinting and Inheritance02:30

Genomic Imprinting and Inheritance

37.2K
Diploid organisms inherit genetic material through chromosomes from both parents. Copies of the same gene are known as alleles. In most cases, both alleles are simultaneously expressed and allow various cellular processes to function optimally. If one of the alleles is missing or mutated, the expression of the other allele can compensate; however, this is not true for all genes.
The expression of some genes depends on which parent passed the gene to the offspring, through a phenomenon known as...
37.2K
Genome Size and the Evolution of New Genes03:21

Genome Size and the Evolution of New Genes

9.2K
While every living organism has a genome of some kind (be it RNA, or DNA), there is considerable variation in the sizes of these blueprints. One major factor that impacts genome size is whether the organism is prokaryotic or eukaryotic. In prokaryotes, the genome contains little to no non-coding sequence, such that genes are tightly clustered in groups or operons sequentially along the chromosome. Conversely, the genes in eukaryotes are punctuated by long stretches of non-coding sequence.
9.2K
Cis-regulatory Sequences02:02

Cis-regulatory Sequences

11.9K
Cis-regulatory sequences are short fragments of non-coding DNA that are present on the same chromosomes as the genes that they regulate. These fragments serve as binding sites for transcriptional regulators, proteins that are responsible for controlling gene transcription and differential gene expression across cell types in eukaryotes. Cis-regulatory sequences can be close to the gene of interest or thousands of bases away in the DNA sequence; however, those sequences that are further away are...
11.9K
Comparing Mitochondrial, Chloroplast, and Prokaryotic Genomes02:16

Comparing Mitochondrial, Chloroplast, and Prokaryotic Genomes

16.4K
The present-day mitochondrial and chloroplast genomes have retained some of the characteristics of their ancestral prokaryotes and also have acquired new attributes during their evolution within eukaryotic cells. Like prokaryotic genomes, mitochondrial and chloroplast genomes neither bind with histone-like proteins nor show complex packaging into chromosome-like structures, as observed in eukaryotes. Unlike mitotic cell divisions observed in eukaryotic cells, mitochondria and chloroplasts...
16.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A multifunctional porous interface bridging 3D architected electronics with skin.

Science advances·2026
Same author

Incarcerated prolapsed ureterocele masquerading as a vulvar mass after midurethral sling surgery: a case report with systematic review.

Frontiers in surgery·2026
Same author

Effect of thalidomide on sporadic central nervous system arteriovenous malformations.

Science bulletin·2026
Same author

Rhododendron mariae Hance protects against dengue virus infection by targeting viral entry and modulating host-pathogen interactions.

Microbial pathogenesis·2026
Same author

Phase-selective Floquet engineering in a charge density wave material.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

External and Internal Cultivation Strategy toward Ultra-Bright Lanthanide Nano-Bioprobes.

Journal of the American Chemical Society·2026

Related Experiment Video

Updated: Feb 8, 2026

Ultra-long Read Sequencing for Whole Genomic DNA Analysis
10:34

Ultra-long Read Sequencing for Whole Genomic DNA Analysis

Published on: March 15, 2019

24.0K

[Canine Circovirus Genome Cloning and Sequence Analysis].

Wenchao Sun, Huihui Cao, Min Zheng

    Bing Du Xue Bao = Chinese Journal of Virology
    |July 7, 2018
    PubMed
    Summary
    This summary is machine-generated.

    A new Chinese dog circovirus (DogCV) isolate was sequenced, revealing its genome structure and genetic diversity. This study provides insights into DogCV evolution and global spread.

    More Related Videos

    Detection of Rare Genomic Variants from Pooled Sequencing Using SPLINTER
    14:06

    Detection of Rare Genomic Variants from Pooled Sequencing Using SPLINTER

    Published on: June 23, 2012

    15.7K
    Novel Sequence Discovery by Subtractive Genomics
    09:40

    Novel Sequence Discovery by Subtractive Genomics

    Published on: January 25, 2019

    9.1K

    Related Experiment Videos

    Last Updated: Feb 8, 2026

    Ultra-long Read Sequencing for Whole Genomic DNA Analysis
    10:34

    Ultra-long Read Sequencing for Whole Genomic DNA Analysis

    Published on: March 15, 2019

    24.0K
    Detection of Rare Genomic Variants from Pooled Sequencing Using SPLINTER
    14:06

    Detection of Rare Genomic Variants from Pooled Sequencing Using SPLINTER

    Published on: June 23, 2012

    15.7K
    Novel Sequence Discovery by Subtractive Genomics
    09:40

    Novel Sequence Discovery by Subtractive Genomics

    Published on: January 25, 2019

    9.1K

    Area of Science:

    • Veterinary Virology
    • Molecular Biology
    • Genomics

    Background:

    • Dog circovirus (DogCV) is an emerging circovirus affecting dogs.
    • Understanding its genomic characteristics and genetic diversity is crucial for disease management.

    Purpose of the Study:

    • To determine the full genome sequence of a Chinese DogCV isolate.
    • To analyze the genomic organization and genetic diversity of this isolate.
    • To compare it with other global DogCV strains.

    Main Methods:

    • Overlap PCR was used to amplify the DogCV genome from dog serum DNA.
    • Nucleotide content and genome organization were analyzed.
    • Phylogenetic analysis was performed on the Rep and Cap genes.

    Main Results:

    • The full genome of the Chinese isolate JZ98/2014 is 2063 nucleotides long.
    • It contains three major open reading frames (ORFs) encoding Rep, Cap, and a 106-amino acid protein.
    • The Chinese isolate showed 82.1%-89.5% homology with other global DogCV isolates and formed a distinct phylogenetic clade.

    Conclusions:

    • The JZ98/2014 isolate represents a unique genetic lineage of DogCV.
    • This finding contributes to understanding the global genetic diversity and evolution of DogCV.