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Comparison of the 2017 Taiwan lipid guidelines and the Western lipid guidelines for high risk patients
Yi-Heng Li1, Hung-I Yeh2, Jiann-Shing Jeng3
1Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan, ROC.
Insights
The 2017 Taiwan lipid guidelines for high-risk patients align with Western guidelines but offer unique recommendations based on Asian studies. These guidelines aim to manage dyslipidemia and reduce atherosclerotic cardiovascular disease (ASCVD) risk.
Area of Science:
- Cardiology
- Endocrinology
- Public Health
Background:
- Dyslipidemia is a primary driver of atherosclerotic cardiovascular disease (ASCVD).
- Existing lipid guidelines predominantly originate from Western countries, focusing on lipid reduction via lifestyle and pharmacotherapy.
- High-risk populations, including those with existing ASCVD, diabetes, chronic kidney disease, and familial hypercholesterolemia, require tailored management strategies.
Purpose of the Study:
- To compare the 2017 Taiwan lipid guidelines for high-risk patients with Western guidelines.
- To identify similarities and differences in managing dyslipidemia in individuals at high risk for ASCVD.
- To specifically examine variations in defining high-risk groups and setting treatment goals for ASCVD risk reduction.
Main Methods:
- Comparative review of the 2017 Taiwan lipid guidelines and major Western lipid guidelines.
- Analysis of recommendations for high-risk patient populations.
- Focus on definitions of high-risk groups and treatment targets for ASCVD risk reduction.
Main Results:
- The 2017 Taiwan guidelines largely concur with Western guidelines for high-risk patients.
- Notable differences exist, influenced by Asian-originated studies and local expert consensus.
- Specific variations were observed in the definition of high-risk populations and treatment goals.
Conclusions:
- The 2017 Taiwan lipid guidelines provide a valuable regional perspective on managing dyslipidemia in high-risk ASCVD patients.
- Understanding these differences is crucial for optimizing ASCVD prevention strategies globally.
- The guidelines emphasize the importance of culturally and regionally relevant evidence in clinical practice.
Abstract:
Dyslipidemia is a major contributor in initiation, development and progression of atherosclerotic cardiovascular disease (ASCVD). Most lipid guidelines are from Europe and America and centered on the reduction of atherogenic lipids levels through lifestyle intervention and pharmacotherapy. Recently, the 2017 Taiwan lipid guidelines for high risk patients was published to facilitate the control of dyslipidemia in patients that are highly susceptible to ASCVD, including patients with preexisting ASCVD, diabetes, chronic kidney disease and familial hypercholesterolemia. Most recommendations outlined in the 2017 Taiwan lipid guidelines for high risk patients are in concordance with those of Western guidelines. However, based on evidence from the studies originating from Asia and local expert opinions, there are some recommendations different from the other guidelines. The purpose of the current review is to compare the similarities and differences between the perspectives of the 2017 Taiwan lipid guidelines for high risk patients and other Western guidelines in individuals at high risk of ASCVD. The definitions of high risk groups and treatment goals defined to achieve ASCVD risk reduction are specifically compared.
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