Related Experiment Video
Updated: Feb 8, 2026
Ultrasonography of the Adult Male Urinary Tract for Urinary Functional Testing
Published on: August 14, 2019
High prevalence of pediatric urinary tract stones in Xinjiang Uyghur
Jian Huang1, Hamulati Tusong2, Abudukahaer Batuer3
1Department of Urology, Minimally Invasive Surgery Center, Guangzhou Institute of Urology, Guangdong Key Laboratory of Urology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510230, Guangdong, China.
Insights
Urolithiasis (kidney stones) in Uyghur patients shows calcium oxalate is most common, but ammonium urate is high in children under one. Pediatric urolithiasis is a significant concern in this population.
Area of Science:
- Nephrology
- Urology
- Public Health
Background:
- Urolithiasis prevalence and stone composition vary significantly across different ethnicities and geographic regions.
- Understanding these variations is crucial for targeted prevention and treatment strategies.
Purpose of the Study:
- To characterize the epidemiological and etiological features of urolithiasis in the Uyghur population of Xinjiang, China.
- To identify specific stone compositions and demographic patterns within this ethnic group.
Main Methods:
- Analysis of kidney stone composition from 1863 Uyghur patients in Xinjiang.
- Demographic data including age and sex were collected and analyzed.
- Statistical analysis was performed to identify trends and significant differences.
Main Results:
- Calcium oxalate was the most frequent stone type (42.1%), followed by ammonium urate (20.6%).
- Pediatric patients (0-18 years) constituted 51.5% of cases, with a peak incidence in children aged 1-2 years.
- Ammonium urate stones were highly prevalent in infants under one year (52.4%), decreasing with age, while uric acid stones showed an age-related trend reversal between pediatric and adult groups.
Conclusions:
- Urolithiasis in Xinjiang Uyghur patients exhibits distinct characteristics, notably a high prevalence of pediatric cases and significant rates of ammonium urate stones in infants.
- The findings highlight the need for tailored management approaches for urolithiasis in this population, with a particular focus on pediatric stone disease.
Abstract:
The aim of the study was to report the characteristics of urolithiasis in Uyghur patients from Xinjiang, China. The composition of stones collected from 1863 patients in the Uyghur region of Xinjiang was analyzed. The median age of patients was 17 years [25th and 75th percentiles: 2, 36]. The stones were delivered by 1299 males (69.7%) and 564 females (30.3%). Calcium oxalate was the predominant stone component in 42.1% of the patients, followed by ammonium urate in 20.6%. Females had formed more stones of magnesium ammonium phosphate 8.9 vs. 5.6% (p = 0.010) and carbonate apatite 6.2 vs. 3.3% (p = 0.004). In contrast uric acid was more common in males than in females; 21.6 vs. 15.1% (p = 0.001). In this series, pediatric patients (age range 0-18) were more likely to present with a stone (51.5%, p < 0.001). Moreover, the largest number of pediatric stones was recorded in children 1-2 years old (37.9%, p < 0.001). The occurrence of ammonium urate stones was extremely high (52.4%) in children with an age below 1 year. There was a downward trend for ammonium urate with age in both children and adults (p for trend < 0.001, respectively). In contrast the frequency of uric acid declined with age in pediatric patients, but increased in adults (p for trend < 0.001, respectively). This study provides a basis for further considerations on the management of Xinjiang Uyghur patients and emphasize the severity of pediatric stone problems.
Related Concept Videos
01:28Urinary Tract Calculi I: Introduction
01:26Urinary Tract Infection I: Introduction
01:25Urinary Tract Infection II: Pathophysiology
01:28Urinary Tract Calculi V: Nursing Management
01:25Urinary Tract Calculi VI: Surgical Management
01:17Urinary Tract Infection IV: Nursing Management