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Delayed Healing Associated with Silver Sulfadiazine Use for Partial Thickness Scald Burns in Children

Steven L Raymond, Antonia Zecevic, Shawn D Larson

    The American Surgeon
    |July 9, 2018
    PubMed

    Insights

    Silver sulfadiazine dressings prolong healing time for pediatric scald burns. Biosynthetic dressings or topical antimicrobial ointments are recommended for better outcomes in children with burns.

    Area of Science:

    • Pediatric burn care
    • Wound healing research
    • Dermatological treatments

    Background:

    • Burns are a significant cause of pediatric injury.
    • Current management of pediatric burns lacks a unified treatment consensus.
    • Partial-thickness scald burns require effective wound management strategies.

    Purpose of the Study:

    • To compare the healing outcomes of three distinct dressings for pediatric partial-thickness scald burns.
    • To evaluate the efficacy of topical antimicrobial ointment, silver sulfadiazine, and biosynthetic dressings.
    • To identify optimal dressing choices for improving pediatric burn healing.

    Main Methods:

    • Retrospective, single-center study of pediatric patients (0-16 years) with acute partial-thickness scald burns.
    • Data collected on prehospital, inpatient, and outpatient care from July 2007 to December 2012.
    • Cohort analysis stratified by dressing type: topical antimicrobial (TA) ointment, silver sulfadiazine (SS), and biosynthetic dressing (BD).

    Main Results:

    • 177 patients met study criteria; mean burn size was 8.3% total body surface area.
    • Silver sulfadiazine (SS) treatment resulted in significantly longer healing times compared to TA and BD.
    • Patients treated with SS also required more compression garments for scar therapy.

    Conclusions:

    • Silver sulfadiazine dressings are associated with delayed healing and increased scarring risk in pediatric partial-thickness scald burns.
    • Biosynthetic dressings and topical antimicrobial ointments demonstrate superior outcomes.
    • Clinical practice has been updated to favor biosynthetic or topical antimicrobial dressings for pediatric burn management.

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