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The Effect of Methylphenidate on the Hearing of Children with Attention Deficit Hyperactivity Disorder

Onur İsmi1, Veli Yildirim2, Yusuf Vayisoglu1

  • 1Department of Otorhinolaryngology, Mersin Üniversitesi, Mersin, Turkey.

International Archives of Otorhinolaryngology
|July 10, 2018
PubMed

Insights

Methylphenidate, used for attention deficit hyperactivity disorder (ADHD), was evaluated for hearing side effects. The study found no significant ototoxic effects in pediatric patients after treatment, suggesting it is a safe medication.

Area of Science:

  • Pediatric Neurology
  • Otolaryngology
  • Pharmacology

Background:

  • A case of sudden hearing loss after methylphenidate treatment in a child with attention deficit hyperactivity disorder (ADHD) prompted this investigation.
  • Methylphenidate is a common stimulant medication used to manage ADHD symptoms in children.

Purpose of the Study:

  • To investigate the potential ototoxic side effects of methylphenidate in pediatric patients diagnosed with ADHD.
  • To assess changes in auditory function following methylphenidate treatment.

Main Methods:

  • The study included thirty pediatric patients with ADHD.
  • Auditory function was assessed using pure tone audiometry, speech discrimination tests, and auditory brainstem response (ABR) before and three months after initiating methylphenidate treatment.
  • ABR parameters included absolute and interpeak latencies at 80 dB nHL following click stimuli.

Main Results:

  • No statistically significant differences were observed in pure tone audiometry, speech discrimination scores, or ABR results between pre-treatment and post-treatment assessments (p > 0.05 for all parameters).
  • These findings indicate that methylphenidate treatment did not lead to measurable hearing impairment in the studied pediatric population.

Conclusions:

  • Methylphenidate appears to be a safe medication concerning ototoxic side effects in children with ADHD.
  • Further research with larger cohorts and extended follow-up periods is recommended to corroborate these findings.

Keywords:
attention deficit hyperactivity disorderhearingmethylphenidate

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