Personalizing Radiation Treatment Delivery in the Management of Breast Cancer
Kamran A Ahmed1, G Daniel Grass1, Amber G Orman1
1Department of Radiation Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.
Abstract:
Long-term data establishes the efficacy of radiotherapy in the adjuvant management of breast cancer. New dose and fractionation schemas have evolved and are available, each with unique risks and rewards. Current efforts are ongoing to tailor radiotherapy to the unique biology of breast cancer. In this review, we discuss our efforts to personalize radiotherapy dosing using genomic data and the implications for future clinical trials. We also explore immune mechanisms that may contribute to a tumor's unique radiation sensitivity or resistance.
Related Concept Videos
Treatment Resistant Cancers
Biological Effects of Radiation
Radiation: Applications
The average...
Absorption of Radiation
Radiation Pressure: Problem Solving
The average value of the rate of momentum transfer divided by the absorbing area represents the average force...
Generating Electromagnetic Radiations


