Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Observational Studies01:11

Observational Studies

11.1K
Observational studies are a type of analytical study where researchers observe events without any interventions. In other words, the researcher does not influence the response variable or the experiment's outcome.
There are three types of observational studies – Prospective, retrospective, and cross-sectional.
Prospective Study
Prospective studies, also known as longitudinal or cohort studies, are carried out by collecting future data from groups sharing similar characteristics. One...
11.1K
Imaging Studies I: Kidney, Ureter, and Bladder Studies01:28

Imaging Studies I: Kidney, Ureter, and Bladder Studies

374
Kidney, Ureter, and Bladder (KUB) StudiesKidney, Ureter, and Bladder (KUB) studies are standard diagnostic imaging procedures used to assess the anatomy of the urinary system. They are commonly utilized for patients experiencing abdominal pain or urinary symptoms. By using a simple X-ray of the abdomen, KUB studies can reveal structural and pathological abnormalities within the kidneys, ureters, and bladder. These studies are particularly valuable in diagnosing kidney stones, urinary...
374
Naturalistic Observations02:30

Naturalistic Observations

17.4K
If you want to understand how behavior occurs, one of the best ways to gain information is to simply observe the behavior in its natural context. However, people might change their behavior in unexpected ways if they know they are being observed. How do researchers obtain accurate information when people tend to hide their natural behavior? As an example, imagine that your professor asks everyone in your class to raise their hand if they always wash their hands after using the restroom. Chances...
17.4K
Urinary Bladder01:23

Urinary Bladder

3.5K
The urinary bladder is a hollow, muscular sac that temporarily stores urine before it is expelled from the body. It can hold approximately 600 mL of urine prior to micturition. The bladder is retroperitoneal and located behind the pubic symphysis in the pelvic floor.
In males, the bladder is situated in front of the rectum, while in females, it is positioned anterior to the vagina and uterus. The bladder floor contains an inverted triangular area called the trigone, defined by the two ureteric...
3.5K
Observational Learning01:12

Observational Learning

1000
Albert Bandura's observational learning, also known as imitation or modeling, occurs when a person observes and imitates another's behavior. It is a quicker process than operant conditioning. A well-known example is the Bobo doll study, where children who saw an adult acting aggressively towards the doll were more likely to act aggressively when left alone, compared to those who observed a nonaggressive adult. Many psychologists view observational learning as a form of latent learning...
1000
Actor-Observer Effect01:23

Actor-Observer Effect

404
The actor-observer effect, a cognitive bias closely linked to the fundamental attribution error, refers to the tendency for individuals to attribute their behavior to external, situational factors while explaining others’ behavior in terms of internal, dispositional traits. This asymmetry in attribution significantly influences social perception and judgment.Cognitive Mechanisms Behind the EffectTwo primary psychological mechanisms contribute to the actor-observer effect: differences in...
404

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Influenza immune imprinting synergizes PEI-HA/CpG nanoparticle vaccine protection against heterosubtypic infection in mice.

Vaccine·2023
Same author

ISCOMs/MPLA-Adjuvanted SDAD Protein Nanoparticles Induce Improved Mucosal Immune Responses and Cross-Protection in Mice.

Small (Weinheim an der Bergstrasse, Germany)·2023
Same author

cGAMP-adjuvanted multivalent influenza mRNA vaccines induce broadly protective immunity through cutaneous vaccination in mice.

Molecular therapy. Nucleic acids·2022
Same author

Layered protein nanoparticles containing influenza B HA stalk induced sustained cross-protection against viruses spanning both viral lineages.

Biomaterials·2022
Same author

SARS-CoV-2 Spike Stem Protein Nanoparticles Elicited Broad ADCC and Robust Neutralization against Variants in Mice.

Small (Weinheim an der Bergstrasse, Germany)·2022
Same author

Polycationic HA/CpG Nanoparticles Induce Cross-Protective Influenza Immunity in Mice.

ACS applied materials & interfaces·2022

Related Experiment Video

Updated: Feb 8, 2026

An Orthotopic Bladder Tumor Model and the Evaluation of Intravesical saRNA Treatment
08:43

An Orthotopic Bladder Tumor Model and the Evaluation of Intravesical saRNA Treatment

Published on: July 28, 2012

15.2K

Intravesical electrical stimulation treatment for overactive bladder: An observational study.

J Joshua Yune1, Jim K Shen1, Matthew A Pierce1

  • 1Department of Urology, Loma Linda University Medical Center, Loma Linda, CA, USA.

Investigative and Clinical Urology
|July 10, 2018
PubMed
Summary

Intravesical electrical stimulation (IVES) offers a safe and effective new treatment for overactive bladder (OAB) and urgency urinary incontinence (UUI) in women. This study shows significant symptom improvement and enhanced quality of life after IVES therapy.

Keywords:
Electrical stimulationUrinary bladder, overactiveUrinary incontinence, urge

More Related Videos

The Use of Cystometry in Small Rodents: A Study of Bladder Chemosensation
08:08

The Use of Cystometry in Small Rodents: A Study of Bladder Chemosensation

Published on: August 21, 2012

23.9K
Author Spotlight: Repetitive Transcranial Magnetic Stimulation Combined with Movement Observation in Cerebral Palsy
07:20

Author Spotlight: Repetitive Transcranial Magnetic Stimulation Combined with Movement Observation in Cerebral Palsy

Published on: August 9, 2024

2.0K

Related Experiment Videos

Last Updated: Feb 8, 2026

An Orthotopic Bladder Tumor Model and the Evaluation of Intravesical saRNA Treatment
08:43

An Orthotopic Bladder Tumor Model and the Evaluation of Intravesical saRNA Treatment

Published on: July 28, 2012

15.2K
The Use of Cystometry in Small Rodents: A Study of Bladder Chemosensation
08:08

The Use of Cystometry in Small Rodents: A Study of Bladder Chemosensation

Published on: August 21, 2012

23.9K
Author Spotlight: Repetitive Transcranial Magnetic Stimulation Combined with Movement Observation in Cerebral Palsy
07:20

Author Spotlight: Repetitive Transcranial Magnetic Stimulation Combined with Movement Observation in Cerebral Palsy

Published on: August 9, 2024

2.0K

Area of Science:

  • Urology
  • Gynecology
  • Pelvic Health

Background:

  • Overactive bladder (OAB) and urgency urinary incontinence (UUI) significantly impact women's quality of life.
  • Existing medical therapies for OAB/UUI often have limited efficacy or side effects.
  • Intravesical electrical stimulation (IVES) is an established treatment for neurogenic bladder.

Purpose of the Study:

  • To evaluate the safety and efficacy of IVES for women diagnosed with OAB and/or UUI.
  • To assess patient-reported outcomes and objective measures of bladder function following IVES treatment.
  • To explore IVES as a novel therapeutic option for refractory OAB/UUI in women.

Main Methods:

  • An observational study involving women with OAB/UUI who failed prior medical therapy.
  • Four weeks of treatment using an 8-Fr Detruset™ IVES catheter.
  • Primary outcome: Patient Global Impression of Improvement (PGI-I) at 3 months; Secondary outcomes: OAB-q SF, PFDI, PFIQ, voiding diary parameters, VAS, and adverse events.

Main Results:

  • 15 out of 17 subjects reported improvement in PGI-I at 3 months post-treatment.
  • Significant improvements were observed in OAB symptom bother, quality of life (OAB-q SF), and pelvic floor distress (PFDI).
  • Mean urinary frequency decreased, and no significant pain was reported during IVES; one UTI occurred.

Conclusions:

  • Intravesical electrical stimulation (IVES) demonstrates potential as a safe and effective treatment for overactive bladder (OAB) in women.
  • IVES offers a promising alternative for patients with OAB/UUI refractory to conventional therapies.
  • Further large-scale, comparative studies are warranted to confirm long-term efficacy and optimal use of IVES for OAB/UUI.