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Updated: Feb 8, 2026

A Porcine Model of Acute Autologous Pulmonary Embolism
Published on: September 6, 2024
Successful treatment of massive pulmonary embolism with low-dose tissue plasminogen activator after meniscus surgery
Hicaz Zencirkiran Agus1, Begum Uygur, Arda Guler
1Department of Cardiology, Saglik Bilimleri University Mehmet Akif Ersoy Cardiovascular and Thoracic Surgery Educational and Research Hospital, Istanbul, Turkey.
Abstract:
: Pulmonary embolism is a life-threatening disease which represents with high mortality and morbidity. Systemic fibrinolysis is the first-line recommended therapy in hemodynamically instable patients with massive pulmonary embolism. Systemic fibrinolytic treatment remains controversial for pulmonary embolism after surgery due to high risk of hemorrhage. Herein, we report a 49-year-old man with massive pulmonary embolism after meniscus surgery, successfully treated with low-dose prolonged infusion of tissue type plasminogen activator.
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