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Opioid Therapy in Acute and Chronic Pain
Anne N Nafziger1,2, Robert L Barkin3,4
1Bertino Consulting, Schenectady, NY, USA.
Journal of Clinical Pharmacology
|July 10, 2018
Summary
This article details safe and effective opioid therapy for acute and chronic pain management. It covers essential clinical pharmacology, including dosing, risks, and monitoring, to optimize patient outcomes.
Area of Science:
- Clinical Pharmacology
- Pain Management
Background:
- Opioid therapy is a cornerstone for managing acute and chronic pain.
- Understanding opioid pharmacology is crucial for safe and effective prescribing.
Purpose of the Study:
- To review the principles of safe and effective opioid therapy for acute and chronic pain.
- To discuss key aspects of clinical opioid use, including assessment, dosing, and monitoring.
Main Methods:
- Review of basic pharmacokinetic and pharmacodynamic properties of opioids.
- Discussion of clinical assessment, treatment planning, equianalgesic dosing, opioid rotation, risk management, and adherence monitoring.
- Inclusion of clinical vignettes for practical application.
Main Results:
- Individualized opioid therapy can be a safe and effective part of multimodal pain management.
- Anticipation and recognition of adverse effects and risks are key to prevention and management.
Conclusions:
- Opioid therapy, when individualized and part of a multimodal plan, offers a safe and effective approach to pain management.
- Proactive management of risks and side effects enhances the safety profile of opioid therapy.
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