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Iron deficiency anaemia: experiences and challenges
Isabella Stelle1, Anastasia Z Kalea1,2,3, Dora I A Pereira4,5
1Institute of Liver and Digestive Health, Division of Medicine, University College London, London WC1E 6BT, UK.
Iron deficiency anaemia (IDA) affects 1.24 billion people globally, particularly women and children. Current treatments are ineffective, necessitating new strategies combining community engagement with social science for effective iron deficiency management.
Area of Science:
- Global health and nutrition science focusing on micronutrient deficiencies.
Background:
- Iron deficiency is the most prevalent nutritional deficiency worldwide, leading to iron deficiency anaemia (IDA).
- IDA affects 1.24 billion people, disproportionately impacting children and women in low-resource settings.
- In Sub-Saharan Africa, infections exacerbate iron deficiency, contributing to maternal mortality and impaired child cognitive development.
Framework:
- Existing iron supplementation and fortification programs have yielded limited success in reducing IDA burden over 25 years.
- Current iron compounds offer a non-physiological approach with significant side effects, proving ineffective in populations with high infectious disease prevalence.
Implementation:
- Novel strategies are required to overcome the limitations of current iron interventions.
- Integrating community engagement and social science approaches is crucial for optimizing supplementation and fortification programs.
Implications:
- Effective management of iron deficiency and IDA requires a paradigm shift beyond traditional nutritional interventions.
- A combined approach is essential for the future elimination of iron deficiency as a public health problem.
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