Related Experiment Video

Updated: Feb 8, 2026

Comet Assay to Quantify DNA Damage in FLT3 Mutant-expressing 32D Cells after Exposure to Type I and Type II FLT3 Inhibitors
04:36

Comet Assay to Quantify DNA Damage in FLT3 Mutant-expressing 32D Cells after Exposure to Type I and Type II FLT3 Inhibitors

Published on: October 17, 2025

966

Quizartinib Bests Chemo for FLT3-Mutant AML

    Cancer Discovery
    |July 11, 2018
    PubMed

    Abstract:

    The FLT3 inhibitor quizartinib provided a survival benefit over chemotherapy in a phase III trial of patients with relapsed or refractory FLT3-mutant acute myeloid leukemia. The drug, along with other FLT3 inhibitors, could become a first-line treatment based on results from ongoing studies.

    More Related Videos

    Chemo-enzymatic Synthesis of N-glycans for Array Development and HIV Antibody Profiling
    11:08

    Chemo-enzymatic Synthesis of N-glycans for Array Development and HIV Antibody Profiling

    Published on: February 5, 2018

    9.2K
    Migration, Chemo-Attraction, and Co-Culture Assays for Human Stem Cell-Derived Endothelial Cells and GABAergic Neurons
    10:09

    Migration, Chemo-Attraction, and Co-Culture Assays for Human Stem Cell-Derived Endothelial Cells and GABAergic Neurons

    Published on: January 23, 2020

    7.5K

    Related Experiment Videos

    Last Updated: Feb 8, 2026

    Comet Assay to Quantify DNA Damage in FLT3 Mutant-expressing 32D Cells after Exposure to Type I and Type II FLT3 Inhibitors
    04:36

    Comet Assay to Quantify DNA Damage in FLT3 Mutant-expressing 32D Cells after Exposure to Type I and Type II FLT3 Inhibitors

    Published on: October 17, 2025

    966
    Chemo-enzymatic Synthesis of N-glycans for Array Development and HIV Antibody Profiling
    11:08

    Chemo-enzymatic Synthesis of N-glycans for Array Development and HIV Antibody Profiling

    Published on: February 5, 2018

    9.2K
    Migration, Chemo-Attraction, and Co-Culture Assays for Human Stem Cell-Derived Endothelial Cells and GABAergic Neurons
    10:09

    Migration, Chemo-Attraction, and Co-Culture Assays for Human Stem Cell-Derived Endothelial Cells and GABAergic Neurons

    Published on: January 23, 2020

    7.5K

    Related Concept Videos

    Epistasis01:39

    Epistasis

    50.2K
    In addition to multiple alleles at the same locus influencing traits, numerous genes or alleles at different locations may interact and influence phenotypes in a phenomenon called epistasis. For example, rabbit fur can be black or brown depending on whether the animal is homozygous dominant or heterozygous at a TYRP1 locus. However, if the rabbit is also homozygous recessive at a locus on the tyrosinase gene (TYR), it will have an unshaded coat that appears white, regardless of its TYRP1...
    50.2K
    Multiple Allele Traits01:49

    Multiple Allele Traits

    38.2K
    The Concept of Multiple Allelism
    38.2K
    Protein Complex Assembly02:41

    Protein Complex Assembly

    16.8K
    Proteins can form homomeric complexes with another unit of the same protein or heteromeric complexes with different types.  Most protein complexes self-assemble spontaneously via ordered pathways, while some proteins need assembly factors that guide their proper assembly. Despite the crowded intracellular environment, proteins usually interact with their correct partners and form functional complexes.
    Many viruses self-assemble into a fully functional unit using the infected host cell to...
    16.8K

    Articles linked to this work by shared authors, journal, and citation graph.

    Cellular and molecular mechanisms determining allogeneic CAR T cell rejection and expansion.

    Cancer discovery·2026

    Microplastics and Cancer: Still Searching for Causation.

    Cancer discovery·2026

    Targeting RAS for Pancreatic Cancer Interception.

    Cancer discovery·2026

    The liver niche accelerates, while the lung niche restrains secondary spread of breast cancer.

    Cancer discovery·2026

    Dual Functions of B7-H3-MAPK Signaling Orchestrate Tumor Immunosuppression via Regulating the Plasticity of Myeloid-derived Suppressor Cells and Fibroblasts.

    Cancer discovery·2026

    Phase III Trials Test First-Line Options in Advanced NSCLC.

    Cancer discovery·2026
    See all related articles
    JoVE
    x logofacebook logolinkedin logoyoutube logo
    ABOUT JoVE
    OverviewLeadershipBlogJoVE Help Center
    AUTHORS
    Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
    LIBRARIANS
    TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
    RESEARCH
    JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
    EDUCATION
    JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
    Terms & Conditions of Use
    Privacy Policy
    Policies
    Jove
    Visualize
    Contact Us