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Related Concept Videos

Review and Preview01:10

Review and Preview

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In statistics, several tools are used to interpret the data. Measures of central tendency represent the characteristics of the data, such as mean, median, and mode. Additionally, measures of variance like standard deviation and range are used to find the spread of data from the mean. Relative standing measures the distance between data locations. Commonly used measures of relative standings are percentile, z score, and quartiles.
Percentiles are a type of fractile that partition data into...
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Review and Preview01:13

Review and Preview

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Data are individual items of information obtained from a population or sample. Data may be classified as qualitative (categorical), quantitative continuous, or quantitative discrete. Because it is not practical to measure the entire population in a study, researchers use samples to represent the population. A random sample is a representative group from the population chosen by using a method that gives each individual in the population an equal chance of being included in the sample. Random...
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Standard Enthalpy of Formation02:37

Standard Enthalpy of Formation

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Enthalpy changes are typically tabulated for reactions in which both the reactants and products are at the same conditions. A standard state is a commonly accepted set of conditions used as a reference point for the determination of properties under other different conditions. For chemists, the IUPAC standard state refers to materials under a pressure of 1 bar and solutions at 1 M and does not specify a temperature. Many thermochemical tables list values with a standard state of 1 atm. Because...
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On comparing the reactivity of silver and lead, it is observed that the two ionic species, Ag+ (aq) and Pb2+ (aq), show a difference in their redox reactivity towards copper: the silver ion undergoes spontaneous reduction, while the lead ion does not. This relative redox activity can be easily quantified in electrochemical cells by a property called cell potential. This property is commonly known as cell voltage in electrochemistry, and it is a measure of the energy which accompanies the charge...
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Measurement: Standard Units03:38

Measurement: Standard Units

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Every measurement provides three kinds of information: the size or magnitude of the measurement (a number), a standard of comparison for the measurement (a unit), and an indication of the uncertainty of the measurement. While the number and unit are explicitly represented when a quantity is written, the uncertainty is an aspect of the errors in the measurement results.
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Calculating Standard Free Energy Changes02:49

Calculating Standard Free Energy Changes

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The free energy change for a reaction that occurs under the standard conditions of 1 bar pressure and at 298 K is called the standard free energy change. Since free energy is a state function, its value depends only on the conditions of the initial and final states of the system. A convenient and common approach to the calculation of free energy changes for physical and chemical reactions is by use of widely available compilations of standard state thermodynamic data. One method involves the...
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Standardized Method for Measuring Collection Efficiency from Wipe-sampling of Trace Explosives
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DEB-TACE: a standard review.

Fabio Melchiorre1, Francesca Patella2, Lorenzo Pescatori2

  • 1Diagnostic & Interventional Radiology Service, Sant'Andrea Hospital, Vercelli, Italy.

Future Oncology (London, England)
|July 11, 2018
PubMed
Summary
This summary is machine-generated.

Drug-eluting bead transarterial chemoembolization (DEB-TACE) offers controlled chemotherapy delivery for liver cancer. While not proven superior in efficacy, DEB-TACE may offer safety benefits over conventional TACE.

Keywords:
DEB-TACETACEcTACEembolizationhepatocellular carcinomamicrospheres

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Area of Science:

  • Interventional Radiology
  • Oncology
  • Vascular Surgery

Background:

  • Drug-eluting bead transarterial chemoembolization (DEB-TACE) is an advanced endovascular technique utilizing microspheres for targeted chemotherapy release.
  • DEB-TACE has become a primary treatment for unresectable hepatocellular carcinoma due to its controlled pharmacokinetic profile.

Purpose of the Study:

  • To review available microspheres used in DEB-TACE.
  • To analyze comparative studies on embolotherapy techniques for hepatocellular carcinoma.
  • To clarify the role and optimal use of DEB-TACE in managing hepatocellular carcinoma.

Main Methods:

  • Review of current literature on DEB-TACE technology and microsphere types.
  • Analysis of comparative studies evaluating DEB-TACE versus conventional transarterial chemoembolization (TACE).
  • Synthesis of data regarding efficacy and safety outcomes.

Main Results:

  • No definitive evidence supports DEB-TACE's superiority over conventional TACE in terms of efficacy.
  • Potential safety advantages of DEB-TACE are suggested, particularly with technological advancements.
  • A lack of consensus persists regarding the optimal embolotherapy technique choice.

Conclusions:

  • DEB-TACE is a significant treatment modality for hepatocellular carcinoma, offering controlled drug delivery.
  • Further research and technological innovation are needed to fully establish DEB-TACE's advantages.
  • The choice of embolotherapy technique requires careful consideration of individual patient factors and evolving technologies.