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Published on: June 17, 2025
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Pemphigoid gestationis
Ioannis K Papapanagiotou1, Sotiria Tsagouri1, Chrysa G Liakou1
11st Department of Obstetrics and Gynecology "Alexandra" General Hospital University of Athens Lourou str., P.O. 11528 Athens Greece.
Clinical Case Reports
|July 11, 2018
Summary
Pemphigoid gestationis is a rare autoimmune skin disorder during pregnancy. Standard treatments include topical/oral glucocorticoids and oral antihistamines to manage itching and blisters.
Area of Science:
- Dermatology
- Obstetrics
- Immunology
Background:
- Pemphigoid gestationis (PG) is a rare, specific autoimmune blistering disease of pregnancy.
- It presents with intense pruritus and blistering, impacting maternal and fetal well-being.
- Accurate diagnosis and management are crucial for obstetric care.
Purpose of the Study:
- To review the key aspects of pemphigoid gestationis.
- To highlight diagnostic criteria and therapeutic strategies.
- To emphasize the role of obstetricians in managing this condition.
Main Methods:
- Literature review of pemphigoid gestationis.
- Analysis of clinical presentation, diagnosis, and treatment options.
- Focus on obstetric management guidelines.
Main Results:
- Pemphigoid gestationis is characterized by specific clinical and histological findings.
- Topical and oral glucocorticoids are primary treatments for symptom relief.
- Oral antihistamines can be used as adjunctive therapy.
Conclusions:
- Obstetricians must be aware of pemphigoid gestationis for timely recognition.
- Management focuses on symptomatic relief and preventing complications.
- Multidisciplinary care ensures optimal outcomes for mother and fetus.