Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Peptide Bonds02:43

Peptide Bonds

83.3K
A peptide bond covalently attaches amino acids through a dehydration reaction. One amino acid's carboxyl group and another amino acid's amino group combine, releasing a water molecule. The resulting bond is the peptide bond. The products that such linkages form are peptides. As more amino acids join this growing chain, the resulting chain is a polypeptide. Each polypeptide has a free amino group at one end. This end has the N-terminal, or the amino-terminal, and the other end has a free...
83.3K
Protein Complex Assembly02:41

Protein Complex Assembly

16.8K
Proteins can form homomeric complexes with another unit of the same protein or heteromeric complexes with different types.  Most protein complexes self-assemble spontaneously via ordered pathways, while some proteins need assembly factors that guide their proper assembly. Despite the crowded intracellular environment, proteins usually interact with their correct partners and form functional complexes.
Many viruses self-assemble into a fully functional unit using the infected host cell to...
16.8K
Protein Complex Assembly02:41

Protein Complex Assembly

2.6K
2.6K
Spindle Assembly02:50

Spindle Assembly

4.3K
Spindle assembly occurs through three, often coexisting, pathways – the centrosome-mediated pathway, the chromatin-mediated pathway, and the microtubule-mediated pathway – collectively contributing to form a robust spindle apparatus.
In most cells, centrosomes are the primary microtubule nucleation centers. In the centrosome-mediated pathway, the G2-prophase transition triggers centrosome maturation and increased microtubule nucleation. Progressive nucleation results in a...
4.3K
Oligosaccharide Assembly01:24

Oligosaccharide Assembly

3.7K
Protein glycosylation starts in the ER lumen and continues in the Golgi apparatus. Glycosyltransferases catalyze the addition of sugar molecules or glycosylation of proteins. Usually, these enzymes add sugars to the hydroxyl groups of selected serine or threonine residues to form O-linked glycans or the amino groups of asparagine residues to form N-linked glycans. Different positions on the same polypeptide chain can contain differently linked glycans.
Multiple sugar molecules that may or may...
3.7K
Assembly of Cytoskeletal Filaments01:18

Assembly of Cytoskeletal Filaments

27.9K
Cytoskeletal filaments are polymeric forms of smaller protein subunits. However, individual cytoskeletal filaments may easily disassemble or associate with other similar filaments to form rigid structures. Microfilaments, made of actin monomers, rely on actin-binding proteins to form bundles and create networks of individual actin filaments. Microtubules rely on microtubule-associated proteins (MAPs) to form sturdy cylindrical structures. However, the proteins involved in forming complex...
27.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Self-Assembly Behavior of Amino Acids on Au (111) Surfaces: A Molecular Dynamics Study.

Langmuir : the ACS journal of surfaces and colloids·2026
Same author

Formation of S- and Z-twist supramolecular micro-ropes by peptide stereoisomers.

Nature communications·2026
Same author

CO<sub>2</sub> Conversion by a Metal-Coordinated Single Amino Acid Carbonic Anhydrase Enzyme Mimic.

ACS applied materials & interfaces·2026
Same author

Chemical chaperones at the interface of proteostasis and metabolostasis.

Current opinion in structural biology·2026
Same author

Amyloid-β "Co-assembles" with Coatomer Subunit Delta (δ-COP).

The journal of physical chemistry letters·2026
Same author

Shikimate pathway disruption in yeast induces metabolite self-assembly into toxic aggregates.

The FEBS journal·2026
Same journal

Design Principles for Fluid Molecular Ferroelectrics.

Advanced materials (Deerfield Beach, Fla.)·2026
Same journal

Generating Unconventional Spin-Orbit Torques With Patterned Phase Gradients in Tungsten Thin Films.

Advanced materials (Deerfield Beach, Fla.)·2026
Same journal

An In Situ H<sub>2</sub>S-Activated Plasmonic Nanozyme for Near-Infrared II Photo-Thermoelectric Catalytic Therapy.

Advanced materials (Deerfield Beach, Fla.)·2026
Same journal

A Recyclable and Sustainable Hydroxypropyl Methylcellulose Electrolyte for Electrochromic Devices.

Advanced materials (Deerfield Beach, Fla.)·2026
Same journal

Perovskite Heterostructures for Optoelectronic Applications.

Advanced materials (Deerfield Beach, Fla.)·2026
Same journal

Light-Written Nonvolatile Polarization via Defect-Engineered Charge Trapping.

Advanced materials (Deerfield Beach, Fla.)·2026
See all related articles

Related Experiment Video

Updated: Feb 8, 2026

Self-Assembly of Gamma-Modified Peptide Nucleic Acids into Complex Nanostructures in Organic Solvent Mixtures
08:15

Self-Assembly of Gamma-Modified Peptide Nucleic Acids into Complex Nanostructures in Organic Solvent Mixtures

Published on: June 26, 2020

4.7K

Tailor-Made Functional Peptide Self-Assembling Nanostructures.

Moran Amit1,2, Sivan Yuran3, Ehud Gazit4

  • 1Department of Materials Engineering, Ben Gurion University of the Negev, Beer-Sheva, 84105, Israel.

Advanced Materials (Deerfield Beach, Fla.)
|July 11, 2018
PubMed
Summary
This summary is machine-generated.

Scientists are exploring self-assembled peptide materials for advanced applications. These biomimetic assemblies offer biocompatible, eco-friendly, and cost-effective solutions for coatings, gels, and electronics.

Keywords:
bioelectronicshydrogelsnanostructurespeptidesself-assembly

More Related Videos

Modification and Functionalization of the Guanidine Group by Tailor-made Precursors
09:45

Modification and Functionalization of the Guanidine Group by Tailor-made Precursors

Published on: April 27, 2017

11.2K
ECM Protein Nanofibers and Nanostructures Engineered Using Surface-initiated Assembly
16:33

ECM Protein Nanofibers and Nanostructures Engineered Using Surface-initiated Assembly

Published on: April 17, 2014

13.0K

Related Experiment Videos

Last Updated: Feb 8, 2026

Self-Assembly of Gamma-Modified Peptide Nucleic Acids into Complex Nanostructures in Organic Solvent Mixtures
08:15

Self-Assembly of Gamma-Modified Peptide Nucleic Acids into Complex Nanostructures in Organic Solvent Mixtures

Published on: June 26, 2020

4.7K
Modification and Functionalization of the Guanidine Group by Tailor-made Precursors
09:45

Modification and Functionalization of the Guanidine Group by Tailor-made Precursors

Published on: April 27, 2017

11.2K
ECM Protein Nanofibers and Nanostructures Engineered Using Surface-initiated Assembly
16:33

ECM Protein Nanofibers and Nanostructures Engineered Using Surface-initiated Assembly

Published on: April 17, 2014

13.0K

Area of Science:

  • Biomaterials Science
  • Supramolecular Chemistry
  • Nanotechnology

Background:

  • Noncovalent interactions drive protein folding into functional 3D structures.
  • Studying peptide self-assembly elucidates biological and pathological mechanisms.
  • Recent focus on the applicative potential of self-assembled peptide structures.

Purpose of the Study:

  • Highlight advances in biomimetic supramolecular peptide assemblies.
  • Detail design strategies for functional helical, beta-strand, and monolayer-forming peptides.
  • Showcase emerging applications in ecology, biomedicine, and electronics.

Main Methods:

  • Design of helical peptides for specific functions.
  • Development of beta-strand peptides for self-assembly.
  • Engineering of surface-binding monolayer-forming peptides.

Main Results:

  • Demonstrated utility of peptide assemblies as coatings, gels, and electroactive materials.
  • Provided design guidelines for various peptide architectures.
  • Illustrated diverse applications across multiple scientific fields.

Conclusions:

  • Peptide assemblies offer extraordinary design flexibility.
  • These materials are naturally biocompatible and ecologically friendly.
  • Cost-effective production and market emergence of devices incorporating these biomimetic materials are envisioned.