Related Experiment Video

Updated: Feb 8, 2026

Dual-Dye Optical Mapping of Hearts from RyR2R2474S Knock-In Mice of Catecholaminergic Polymorphic Ventricular Tachycardia
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Dual-Dye Optical Mapping of Hearts from RyR2R2474S Knock-In Mice of Catecholaminergic Polymorphic Ventricular Tachycardia

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Efficacy of ivabradine to control ventricular arrhythmias in catecholaminergic polymorphic ventricular tachycardia

Guy Vaksmann1, Didier Klug2

  • 1Department of Pediatric Cardiology, Hôpital Privé de La Louvière, Lille, France.

Pacing and Clinical Electrophysiology : PACE
|July 11, 2018
PubMed

Insights

Catecholaminergic polymorphic ventricular tachycardia (CPVT) treatment can be challenging due to side effects. Ivabradine offers a well-tolerated therapeutic option for CPVT patients, potentially reducing the need for invasive procedures.

Area of Science:

  • Cardiology
  • Genetics
  • Pharmacology

Background:

  • Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a severe inherited arrhythmia syndrome.
  • Current therapies like nadolol and flecainide have limitations due to side effects and compliance issues.
  • High mortality rates in young individuals underscore the need for effective CPVT management.

Keywords:
catecholaminergic polymorphic ventricular tachycardiaivabradine

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