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Personalized laboratory medicine: a patient-centered future approach
Irena Prodan Žitnik1, Darko Černe1, Irene Mancini2
1Faculty of Pharmacy, University of Ljubljana, Ljubljana, Slovenia.
Clinical Chemistry and Laboratory Medicine
|July 11, 2018
Summary
Personalized medicine optimizes patient treatment using molecular profiles from omics technologies. This approach enables more effective, safer diagnostics and treatments by analyzing marker profiles, not single markers.
Area of Science:
- Biomedical Science
- Medical Diagnostics
- Genomics
Background:
- Traditional medicine relies on population-based evidence for treatment strategies.
- Personalized medicine focuses on optimizing treatment for individual patients.
- Advancements in omics technologies enable molecular profiling of individuals.
Purpose of the Study:
- To highlight the role of personalized laboratory medicine in optimizing patient management.
- To emphasize the shift from single-marker analysis to multi-marker profiling for therapeutic decisions.
- To discuss the potential benefits of personalized medicine in healthcare.
Main Methods:
- Utilizing high-throughput instrumental techniques.
- Applying biostatistics tools and artificial intelligence for data analysis.
- Creating comprehensive molecular profiles of individual patients.
Main Results:
- Personalized medicine analyzes marker profiles, not single markers, for treatment decisions.
- It considers both disease and patient-specific responses to therapy.
- This approach promises more effective and safer treatments with improved patient outcomes.
Conclusions:
- Personalized laboratory medicine is crucial for advancing individualized patient care.
- Enhanced interdisciplinary cooperation within laboratory medicine is necessary to empower its role.
- The integration of omics and AI facilitates a more precise and effective healthcare model.
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