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Successful Resolution of a Large Left Ventricular Thrombus with Rivaroxaban Therapy after Acute Myocardial Infarction

Udit Bhaskar Bhatnagar1, Josh Rezkalla2, Prince Sethi1

  • 1Department of Internal Medicine, University of South Dakota Sanford School of Medicine, Sioux Falls, South Dakota.

South Dakota Medicine : the Journal of the South Dakota State Medical Association
|July 11, 2018
PubMed

Insights

Left ventricular thrombus after heart attack is risky. Novel oral anticoagulants like rivaroxaban show promise for treatment, successfully resolving thrombi in a recent case study.

Area of Science:

  • Cardiology
  • Internal Medicine
  • Pharmacology

Background:

  • Left ventricular (LV) thrombus is a serious complication of acute systolic cardiomyopathy, particularly following anterior myocardial infarction (AMI).
  • LV thrombi significantly increase embolic risk, up to fivefold compared to the general population.
  • Current guidelines recommend vitamin K antagonists for LV thrombi, with limited data on novel oral anticoagulants (NOACs).

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