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Author Correction: Foldamers wave to the ribosome
1Department of Chemistry, Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, USA. alanna.schepartz@yale.edu.
Nature Chemistry
|July 12, 2018
Summary
Foldamers with specific, diverse sequences are essential for ribosome interaction. An alternating sequence with a terminal P monomer is crucial for initiating translation, unlike other sequences.
Area of Science:
- Biochemistry and Molecular Biology
- Synthetic Chemistry
Context:
- News & Views article discussing foldamers and their interaction with the ribosome.
- Previous research highlighted sequence-defined foldamers.
Purpose:
- To correct and clarify critical details within a published News & Views article.
- To ensure accurate representation of foldamer sequence-defined properties and their functional implications.
Summary:
- Corrections were made to the description of foldamer monomer sequences, emphasizing diversity and defined order.
- Specific sequences, particularly alternating patterns with terminal P monomers (e.g., PQPQ), were identified as essential for ribosome binding and translation initiation.
- Structural and tabular data in figures were revised for chemical accuracy and experimental result representation.
Impact:
- Ensures the scientific record accurately reflects the properties and functions of sequence-defined foldamers.
- Clarifies the role of specific foldamer sequences in biological processes like translation.
- Improves the reproducibility and understanding of foldamer research through corrected data and references.
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