Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Base Excision Repair01:54

Base Excision Repair

26.4K
One of the common DNA damages is the chemical alteration of single bases by alkylation, oxidation, or deamination. The altered bases cause mispairing and strand breakage during replication. This type of damage causes minimal change to the DNA double helix structure and can be repaired by the base excision repair (BER) pathways. BER corrects damaged DNA sequences by removing the damaged base and restoring the original base sequence using the complementary strand as a template.
The first step of...
26.4K
Base Excision Repair01:54

Base Excision Repair

5.1K
5.1K
Nucleotide Excision Repair01:08

Nucleotide Excision Repair

40.9K
Overview
40.9K
Nucleotide Excision Repair01:38

Nucleotide Excision Repair

5.2K
DNA Distortion and Damage
Cells are regularly exposed to mutagens—factors in the environment that can damage DNA and generate mutations. UV radiation is one of the most common mutagens and is estimated to introduce a significant number of changes in DNA. These include bends or kinks in the structure, which can block DNA replication or transcription. If these errors are not fixed, the damage can cause mutations, which in turn can result in cancer or disease depending on which sequences are...
5.2K
Long-patch Base Excision Repair01:02

Long-patch Base Excision Repair

8.0K
Since the discovery of the two BER pathways, there has been a debate about how a cell chooses one pathway over the other and the factors determining this selection. Numerous in vitro experiments have pointed out multiple determinants for the sub-pathway selection. These are:
8.0K
Overview of DNA Repair02:25

Overview of DNA Repair

33.8K
In order to be passed through generations, genomic DNA must be undamaged and error-free. However, every day, DNA in a cell undergoes several thousand to a million damaging events by natural causes and external factors. Ionizing radiation such as UV rays, free radicals produced during cellular respiration, and hydrolytic damage from metabolic reactions can alter the structure of DNA. Damages caused include single-base alteration, base dimerization, chain breaks, and cross-linkage.
Chemically...
33.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Digitainers-Digital Space Maintainers: A Review.

International journal of clinical pediatric dentistry·2022
Same author

Pediatric Dental Appointments No-show: Rates and Reasons.

International journal of clinical pediatric dentistry·2018
Same author

Neonatal osteomyelitis: An unusual complication of natal tooth extraction.

Journal of the Indian Society of Pedodontics and Preventive Dentistry·2018
Same author

Comparative Assessment of Oral Health Related Quality of Life of Children Before and After Full Mouth Rehabilitation under General Anaesthesia and Local Anaesthesia.

Journal of clinical and diagnostic research : JCDR·2017
Same author

Impact of malocclusion on oral health-related quality of life in 10-14-year-old children of Mumbai, India.

Contemporary clinical dentistry·2016
Same author

Dental Considerations in the Management of Glanzmann's Thrombasthenia.

International journal of clinical pediatric dentistry·2016

Related Experiment Video

Updated: Feb 8, 2026

Vessel-sparing Excision and Primary Anastomosis
08:09

Vessel-sparing Excision and Primary Anastomosis

Published on: January 7, 2019

12.1K

A Case of Painless Excision.

Ipshita A Suyash1, Rupinder Bhatia2

  • 1Postgraduate Student, Department of Pediatric and Preventive Dentistry, D Y Patil School of Dentistry, Navi Mumbai, Maharashtra, India.

International Journal of Clinical Pediatric Dentistry
|July 12, 2018
PubMed
Summary

Laser treatment effectively removes recurrent oral soft tissue lesions in children. This painless dental procedure alleviates child and parent anxiety associated with oral treatments.

Keywords:
LaserPainless dentistryPeripheral giant cell granulomaSoft tissue lesions.

More Related Videos

Localization, Identification, and Excision of Murine Adipose Depots
08:53

Localization, Identification, and Excision of Murine Adipose Depots

Published on: December 4, 2014

42.1K
Analytical Determination of Mitochondrial Function of Excised Solid Tumor Homogenates
11:32

Analytical Determination of Mitochondrial Function of Excised Solid Tumor Homogenates

Published on: August 6, 2021

3.1K

Related Experiment Videos

Last Updated: Feb 8, 2026

Vessel-sparing Excision and Primary Anastomosis
08:09

Vessel-sparing Excision and Primary Anastomosis

Published on: January 7, 2019

12.1K
Localization, Identification, and Excision of Murine Adipose Depots
08:53

Localization, Identification, and Excision of Murine Adipose Depots

Published on: December 4, 2014

42.1K
Analytical Determination of Mitochondrial Function of Excised Solid Tumor Homogenates
11:32

Analytical Determination of Mitochondrial Function of Excised Solid Tumor Homogenates

Published on: August 6, 2021

3.1K

Area of Science:

  • Pediatric Dentistry
  • Oral Surgery
  • Laser Dentistry

Background:

  • Recurrent soft tissue lesions in the oral cavity are a common concern in pediatric dental patients.
  • Traditional treatments can cause anxiety for children and parents due to pain and discomfort.

Observation:

  • A case report details the use of laser technology for treating recurrent oral soft tissue lesions in a pediatric patient.
  • The laser procedure was observed to be painless, significantly reducing patient and parental anxiety.

Findings:

  • Laser treatment offers a minimally invasive and effective method for excising soft tissue lesions in the pediatric oral cavity.
  • The painless nature of the laser procedure enhances patient cooperation and satisfaction.

Implications:

  • Laser dentistry presents a viable, patient-friendly alternative for managing recurrent oral lesions in children.
  • This approach can improve the overall dental experience for anxious pediatric patients and their families.