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Significance of Perianal Lesion in Pediatric Crohn Disease

Won Seok Jin1, Ji Hyoung Park1, Kyung In Lim1

  • 1Department of Pediatrics, Gachon University Gil Medical Center, Incheon, Korea.

Pediatric Gastroenterology, Hepatology & Nutrition
|July 12, 2018
PubMed

Insights

Pediatric Crohn disease (CD) in Korea frequently involves perianal lesions, often appearing before gastrointestinal symptoms. Early suspicion of CD is crucial in children presenting with perianal issues.

Area of Science:

  • Pediatric Gastroenterology
  • Inflammatory Bowel Disease Research
  • Clinical Epidemiology

Background:

  • Increasing incidence of pediatric Crohn disease (CD) in Korea.
  • Limited data on perianal lesion characteristics in pediatric CD.
  • Need for understanding the presentation of pediatric CD in the Korean population.

Purpose of the Study:

  • Investigate the characteristics of perianal lesions in pediatric CD patients in Korea.
  • Determine the prevalence of perianal lesions, including perforating types.
  • Analyze the relationship between perianal lesions and disease duration/symptom onset.

Main Methods:

  • Retrospective review of medical records for children (age ≤18 years) with confirmed CD.
  • Classification of patients into groups based on the presence/absence of perianal lesions (including skin tags).
  • Further analysis based on the presence/absence of perianal perforating lesions.

Main Results:

  • High prevalence of perianal lesions (78.3%) and perforating lesions (42.0%) in pediatric CD.
  • Longer duration of chief complaints in pediatric CD with any perianal lesions.
  • Perianal symptoms preceded gastrointestinal symptoms in 44.8% of patients with perforating perianal lesions.

Conclusions:

  • Crohn disease should be suspected in children with perianal lesions.
  • Consideration of CD is important even when gastrointestinal symptoms are initially absent.
  • Highlights the significance of perianal manifestations in early pediatric CD diagnosis.
Abstract

Keywords:
ChildCrohn diseasePerianal lesions

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