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Related Concept Videos

What is Gene Expression?01:42

What is Gene Expression?

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Overview
Gene expression is the process in which DNA directs the synthesis of functional products, that is, proteins. Cells can regulate gene expression at various stages. It allows organisms to generate different cell types and enables cells to adapt to internal and external factors.
Genetic Information Flows from DNA to RNA to Protein
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What is Gene Expression?01:36

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A gene is a stretch of DNA that serves as the blueprint for functional RNAs and proteins. Since DNA is comprised  of nucleotides and proteins are comprised of amino acids, a mediator is required to convert the information encoded in DNA into proteins. This mediator is the messenger RNA (mRNA). mRNA copies the blueprint from DNA by a process called transcription. In eukaryotes, transcription occurs in the nucleus by complementary base-pairing with the DNA template. The mRNA is then...
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Chromatin is the massive complex of DNA and proteins packaged inside the nucleus. The complexity of chromatin folding and how it is packaged inside the nucleus greatly influences  access to genetic information. Generally, the nucleus' periphery is considered transcriptionally repressive, while the cell's interior is considered a transcriptionally active area. 
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Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
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Erratum to: RNA-Seq and Expression Arrays: Selection Guidelines for Genome-Wide Expression Profiling.

Jessica Minnier1, Nathan D Pennock2, Qiuchen Guo2

  • 1School of Public Health, Oregon Health and Science University, Portland, OR, USA.

Methods in Molecular Biology (Clifton, N.J.)
|July 12, 2018
PubMed
Summary

Author name corrections were made to the book "Qiuchen Guo" after an initial printing error. The revised version accurately reflects the author's name, ensuring proper attribution and scholarly integrity.

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Area of Science:

  • Bibliographic studies
  • Scholarly publishing

Background:

  • The initial publication of a book contained an unintentional misspelling of the author's name, "Qiuchen Guo."
  • This error impacted the accuracy of attribution and the integrity of the scholarly record.

Purpose of the Study:

  • To rectify the misspelling of the author name "Qiuchen Guo."
  • To ensure accurate author attribution in the published work.

Main Methods:

  • A correction was issued for the author's name.
  • The corrected spelling was approved by the author, "Qiuchen Guo."

Main Results:

  • The book's author name has been corrected to "Qiuchen Guo."
  • The author has approved the spelling correction.

Conclusions:

  • The publication error has been resolved.
  • Accurate author attribution is now ensured for "Qiuchen Guo."
  • Scholarly and bibliographic records are now accurate.