Solid-phase synthesis of peptides containing aminoadipic semialdehyde moiety and their cyclisations

Monika Kijewska1, Mateusz Waliczek2, Marta Cal2

  • 1Faculty of Chemistry, University of Wrocław, Joliot-Curie 14, 50-383, Wrocław, Poland. monika.kijewska@chem.uni.wroc.pl.

Scientific Reports
|July 12, 2018
PubMed
Summary

Researchers developed a new method for synthesizing carbonylated peptides using Fmoc-Aea-OH. This approach aids in studying oxidative stress (OS) by creating modified peptides, overcoming challenges with low oxidation product concentrations.

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