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Related Experiment Video

Updated: Feb 8, 2026

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility
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A treatment algorithm for healthy young men with erectile dysfunction.

Adam Wiggins1, Peter N Tsambarlis1, George Abdelsayed1

  • 1Department of Urology, Rush University Medical Center, Chicago, IL, USA.

BJU International
|July 12, 2018
PubMed
Summary

This study shows that a treatment algorithm combining phosphodiesterase type 5 inhibitors and psychosexual therapy is effective for young men with erectile dysfunction (ED) without an organic cause, significantly improving their erectile function and satisfaction.

Keywords:
#ErectileDysfunctionpsychosexual therapytreatment, PDE-5 inhibitoryoung men

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Area of Science:

  • Urology
  • Andrology
  • Sexual Medicine

Background:

  • Erectile dysfunction (ED) in men under 40 without identifiable organic causes presents a unique clinical challenge.
  • Understanding baseline characteristics of this cohort is crucial for effective management.

Purpose of the Study:

  • To assess the baseline characteristics of young men (<40 years) diagnosed with ED with no apparent organic etiology.
  • To evaluate the efficacy of a specific treatment algorithm for this patient group.

Main Methods:

  • Retrospective chart review of 73 men aged <40 with ED and no organic cause.
  • Standard treatment involved daily low-dose phosphodiesterase type 5 inhibitors and psychosexual therapy.
  • Follow-up assessment after a minimum of 6 months using questionnaires.

Main Results:

  • Significant improvement in erectile function (IIEF scores: 18.8 vs 13.3, P < 0.01) and overall satisfaction (6.1 vs 4.5, P < 0.01).
  • Reduction in reported erectile difficulties from 85% to 42% post-treatment.
  • No significant improvement in sexual desire or intercourse satisfaction.

Conclusions:

  • The proposed treatment algorithm is an effective first-line approach for young men with non-organic ED.
  • This management strategy offers a useful framework for urologists treating this demographic.
  • Improved patient-reported outcomes and IIEF scores support the algorithm's efficacy.