Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Application of Linearization and Approximation01:29

Application of Linearization and Approximation

36
A drone flying through complex terrain often relies on more than one sensing method to estimate small changes in altitude. Along with direct measurements, air pressure provides a useful indirect indicator of vertical movement. Atmospheric pressure decreases as altitude increases, and this relationship is commonly described using an exponential model. Although accurate, converting pressure measurements into altitude values requires calculations that are too complex to perform repeatedly during...
36
Application of Nonlinear Inequalities01:29

Application of Nonlinear Inequalities

210
A nonlinear inequality describes a comparison involving an expression that curves or behaves more complexly than a straight line. These inequalities often appear in forms that include squares, products, or variables in the denominator.To solve such an inequality, one starts by rewriting it so that zero appears on one side. For example, the inequality:  can be factored as: This form makes it easier to identify the values that cause the expression to equal zero. In this case, the...
210
Mechanistic Models: Compartment Models in Algorithms for Numerical Problem Solving01:29

Mechanistic Models: Compartment Models in Algorithms for Numerical Problem Solving

282
Mechanistic models play a crucial role in algorithms for numerical problem-solving, particularly in nonlinear mixed effects modeling (NMEM). These models aim to minimize specific objective functions by evaluating various parameter estimates, leading to the development of systematic algorithms. In some cases, linearization techniques approximate the model using linear equations.
In individual population analyses, different algorithms are employed, such as Cauchy's method, which uses a...
282
Residuals and Least-Squares Property01:11

Residuals and Least-Squares Property

9.0K
The vertical distance between the actual value of y and the estimated value of y. In other words, it measures the vertical distance between the actual data point and the predicted point on the line
If the observed data point lies above the line, the residual is positive, and the line underestimates the actual data value for y. If the observed data point lies below the line, the residual is negative, and the line overestimates the actual data value for y.
The process of fitting the best-fit...
9.0K
Calibration Curves: Linear Least Squares01:20

Calibration Curves: Linear Least Squares

4.1K
A calibration curve is a plot of the instrument's response against a series of known concentrations of a substance. This curve is used to set the instrument response levels, using the substance and its concentrations as standards. Alternatively, or additionally, an equation is fitted to the calibration curve plot and subsequently used to calculate the unknown concentrations of other samples reliably.
For data that follow a straight line, the standard method for fitting is the linear...
4.1K
Routh-Hurwitz Criterion II01:19

Routh-Hurwitz Criterion II

940
In the application of the Routh-Hurwitz criterion, two specific scenarios can arise that complicate stability analysis.
The first scenario occurs when a singular zero appears in the first column of the Routh table. This situation creates a division by zero issues. To resolve this, a small positive or negative number, denoted as epsilon (∈), is substituted for the zero. The stability analysis proceeds by assuming a sign for ∈. If ∈ is positive, any sign change in the first...
940

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Epigallocatechin Gallate (EGCG) Inhibits Singapore Grouper Iridovirus (SGIV) Infection by Interfering With Viral Life Cycle and Modulating Host Cell Cycle G2/M Checkpoint.

Journal of fish diseases·2026
Same author

Highly Efficient Nitrogen Removal by <i>Stutzerimonas stutzeri</i> Strain MJ20: Metabolic Pathways and Potential for Biofloc Systems and Low C/N Ratio Aquaculture Wastewater.

Microorganisms·2026
Same author

Gyrodactylus abbottinae n. sp. (Monopisthocotylea: Gyrodactylidae) from Chinese false gudgeon, Abbottina rivularis (Cyprinidae, Gobioninae).

Systematic parasitology·2026
Same author

Diagnosis and Treatment of Foot Fusarium Infection Confirmed by Molecular Identification: A Case Report and Literature Review.

Clinical case reports·2026
Same author

Influence of the degree of context reactivation on retrieval-induced enhancement: A behavioral experiment.

Acta psychologica·2026
Same author

Effect of sodium lactate on the gel quality of cold-stored <i>Litopenaeus vannamei</i>: Perspective of 4D-DIA proteomics.

Food chemistry: X·2026
Same journal

Granular Ball-Based Noise-Resistant Fuzzy Multineighborhood Feature Selection via Label Enhancement and Feature Graph.

IEEE transactions on neural networks and learning systems·2026
Same journal

Fighting Evolving Spam With ARTMAP Models: A Noise-Resilient Online Detection Framework.

IEEE transactions on neural networks and learning systems·2026
Same journal

HyperSAT: Unsupervised Hypergraph Neural Networks for Weighted MaxSAT Problems.

IEEE transactions on neural networks and learning systems·2026
Same journal

Negation of Basic Belief Assignment in Multisource Information Fusion on Dempster-Shafer Theory With Applications in Pattern Classification.

IEEE transactions on neural networks and learning systems·2026
Same journal

Intervention Feasible Region and Driver Risk Capacity Aware Human-Machine Collaborative Safe Trajectory Planning.

IEEE transactions on neural networks and learning systems·2026
Same journal

A Unified Differential Denoising Learning Framework With a Pre-Trained Model and Fuzzy Graph Networks for Drug-Drug Interaction Prediction.

IEEE transactions on neural networks and learning systems·2026
See all related articles

Related Experiment Video

Updated: Jan 14, 2026

Assisted Selection of Biomarkers by Linear Discriminant Analysis Effect Size LEfSe in Microbiome Data
04:57

Assisted Selection of Biomarkers by Linear Discriminant Analysis Effect Size LEfSe in Microbiome Data

Published on: May 16, 2022

17.3K

Modified Sparse Linear-Discriminant Analysis via Nonconvex Penalties.

Jia Cai, Xiaolin Huang

    IEEE Transactions on Neural Networks and Learning Systems
    |July 12, 2018
    PubMed
    Summary
    This summary is machine-generated.

    This study explores sparse linear-discriminant analysis (LDA) using novel nonconvex penalties. These methods improve classification accuracy in high-dimensional, limited-data scenarios like gene expression analysis.

    More Related Videos

    ARL Spectral Fitting as an Application to Augment Spectral Data via Franck-Condon Lineshape Analysis and Color Analysis
    07:11

    ARL Spectral Fitting as an Application to Augment Spectral Data via Franck-Condon Lineshape Analysis and Color Analysis

    Published on: August 19, 2021

    3.0K
    O-cresol Concentration Online Measurement Based On Near Infrared Spectroscopy Via Partial Least Square Regression
    06:50

    O-cresol Concentration Online Measurement Based On Near Infrared Spectroscopy Via Partial Least Square Regression

    Published on: November 8, 2019

    7.0K

    Related Experiment Videos

    Last Updated: Jan 14, 2026

    Assisted Selection of Biomarkers by Linear Discriminant Analysis Effect Size LEfSe in Microbiome Data
    04:57

    Assisted Selection of Biomarkers by Linear Discriminant Analysis Effect Size LEfSe in Microbiome Data

    Published on: May 16, 2022

    17.3K
    ARL Spectral Fitting as an Application to Augment Spectral Data via Franck-Condon Lineshape Analysis and Color Analysis
    07:11

    ARL Spectral Fitting as an Application to Augment Spectral Data via Franck-Condon Lineshape Analysis and Color Analysis

    Published on: August 19, 2021

    3.0K
    O-cresol Concentration Online Measurement Based On Near Infrared Spectroscopy Via Partial Least Square Regression
    06:50

    O-cresol Concentration Online Measurement Based On Near Infrared Spectroscopy Via Partial Least Square Regression

    Published on: November 8, 2019

    7.0K

    Area of Science:

    • Machine Learning
    • Statistical Analysis
    • Bioinformatics

    Background:

    • Linear-discriminant analysis (LDA) is crucial for classification.
    • Undersampled situations (high features, low observations) pose challenges for LDA.
    • Existing sparse LDA methods often rely on L1-norm, limiting flexibility.

    Purpose of the Study:

    • To investigate nonconvex penalties for sparse LDA in undersampled settings.
    • To analyze L0-based and sorted L1-based LDA methods.
    • To evaluate the performance of these novel algorithms on real-world data.

    Main Methods:

    • Developed and analyzed LDA algorithms utilizing L0-based and sorted L1-based nonconvex penalties.
    • The sorted L1-penalty acts as an intermediate between L0 and L1 penalties.
    • Evaluated algorithm performance on gene expression and face databases.

    Main Results:

    • Nonconvex penalty-based LDA methods demonstrate high classification accuracy.
    • These algorithms are effective in undersampled, high-dimensional scenarios.
    • The sorted L1-penalty offers a promising approach bridging L0 and L1 sparsity.

    Conclusions:

    • Nonconvex penalties offer an effective alternative for sparse LDA in undersampled data.
    • The proposed L0-based and sorted L1-based LDA methods achieve superior performance.
    • These findings have implications for classification tasks in fields like bioinformatics.