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Updated: Feb 7, 2026

Sound Source Localization Testing in Single-sided Deafness Following Bone Conduction Intervention
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Round Window Occlusion Affects Bone Conduction in Cadaver Heads.

Keguang Chen1, Huiying Lyu1, Dongming Yin1

  • 1Department of Otorhinolaryngology Head and Neck Surgery, Eye and ENT Hospital, Fudan University.

Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [And] European Academy of Otology and Neurotology
|July 12, 2018
PubMed
Summary

Ear mold glue effectively immobilizes the round window niche for round window occlusion (RWO) models. This RWO procedure impacts bone conduction (BC) hearing thresholds, particularly at 4 kHz, mimicking aspects of otosclerosis.

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Area of Science:

  • Otolaryngology
  • Auditory Physiology
  • Biomedical Engineering

Background:

  • Round window occlusion (RWO) is a surgical technique used in auditory research and treatments.
  • Understanding the impact of RWO on bone conduction (BC) is crucial for auditory function assessment.
  • The feasibility of using specific materials for RWO modeling requires investigation.

Purpose of the Study:

  • To assess the feasibility of using ear mold glue for creating round window occlusion (RWO) models in cadaveric specimens.
  • To investigate the effects of RWO on bone conduction (BC) hearing thresholds using laser Doppler vibrometry.

Main Methods:

  • Ten cadaver heads were utilized to create RWO models.
  • Ear mold glue was employed to immobilize the round window niche.
  • Stapes footplate vibration (VST) and cochlear promontory vibration (VCP) were measured pre- and post-RWO using laser Doppler vibrometry under acoustic and B-71 stimulation.

Main Results:

  • Significant decreases in stapes footplate velocities were observed post-RWO, particularly at higher frequencies (above 4 kHz).
  • The relative vibration of the stapes footplate to the cochlear promontory (VST/VCP) showed minimal change overall.
  • A notable decrease in VST/VCP was recorded at 4 kHz post-RWO, indicating a specific frequency-dependent effect.

Conclusions:

  • Ear mold glue is a viable material for immobilizing the round window niche in cadaveric RWO models.
  • RWO significantly affects bone conduction hearing thresholds, with a characteristic depression at 4 kHz.
  • The observed effects of RWO on BC thresholds share similarities with those seen in otosclerosis.