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Developing a Case-Based Blended Learning Ecosystem to Optimize Precision Medicine: Reducing Overdiagnosis and

Vivek Podder1, Binod Dhakal2, Gousia Ummae Salma Shaik3

  • 1Department of Internal Medicine, Tairunnessa Memorial Medical College, Gazipur 1704, Bangladesh. drvivekpodder@gmail.com.

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Summary

This study explores how case-based blended learning ecosystems (CBBLE) can integrate traditional precision medicine with modern omics approaches. CBBLEs help reduce overdiagnosis and overtreatment by enhancing precision in healthcare.

Keywords:
CBBLE (case-based-based blended learning ecosystem)case studieshigh resource settinglow resource settingomics drivenoverdiagnosisovertreatmentprecision medicine

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Area of Science:

  • Medical Education
  • Precision Medicine
  • Global Health

Background:

  • Precision medicine aims to tailor treatments to individual patients for optimal outcomes.
  • Overdiagnosis and overtreatment are significant challenges in current healthcare systems.
  • Bridging traditional precision approaches with modern omics-driven strategies is crucial.

Purpose of the Study:

  • To present a novel perspective on precision medicine through case-based blended learning ecosystems (CBBLE).
  • To illustrate how CBBLEs can reduce overdiagnosis and overtreatment.
  • To explore the integration of traditional and omics-driven precision medicine.

Main Methods:

  • A series of cases were examined within a CBBLE framework.
  • Case-based narratives from global students in high and low-resource settings were collected and analyzed.
  • Thematic analysis and critical appraisal of narratives were employed.

Main Results:

  • Four micro-narratives demonstrated age-old precision concepts.
  • Four macro-narratives from CBBLE learners showcased their learning journeys.
  • Learner narratives highlighted the progression from basic precision to omics-driven approaches.

Conclusions:

  • CBBLEs effectively integrate traditional and omics-driven precision medicine.
  • Case-based narratives illustrate the value of CBBLE in diverse global health settings.
  • Judicious application of precision medicine strategies via CBBLE can mitigate over/undertreatment and over/underdiagnosis.